Evidence map›Paper›PMID 38215185›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Decoupled evolution of the

Ben R Hopkins, Aidan Angus-Henry, Bernard Y Kim, Jolie A Carlisle, Ammon Thompson, Artyom Kopp

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Correlated Gene Copy Number Changes in a Seminal Fluid Protein Network inbioRxiv : the preprint server for biology · 2025
    Article
  6. Molecular evolution of octopamine receptors inbioRxiv : the preprint server for biology · 2025
    Article
  7. Gene age shapes functional and evolutionary properties of theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Female membrane proteins regulate postmating ovulation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Is variation in female aggressiveness acrossProceedings. Biological sciences · 2025
    Article
  11. Article
  12. Article
  13. Regional specialization, polyploidy, and seminal fluid transcripts in theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ben R HopkinsDepartment of Evolution and Ecology, University of California, Davis, CA 95616.ORCID 0000-0002-9760-6185
Aidan Angus-HenryDepartment of Evolution and Ecology, University of California, Davis, CA 95616.ORCID 0009-0004-0427-3732
Bernard Y KimDepartment of Biology, Stanford University, Stanford, CA 94305.
Jolie A CarlisleDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.
Ammon ThompsonDepartment of Evolution and Ecology, University of California, Davis, CA 95616.ORCID 0000-0003-1825-4685
Artyom KoppDepartment of Evolution and Ecology, University of California, Davis, CA 95616.ORCID 0000-0001-5224-0741

Funding

New Targets for Reproductive Control of Mosquito VectorsR01AI095491 · NIAID · CORNELL UNIVERSITY · PI Laura C Harrington, Mariana Federica Wolfner · 2011 to 2026
$7.3M
Molecular Genetics of Evolutionary InnovationsR35GM122592 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ARTYOM KOPP · 2017 to 2026
$4.5M
Actions of Seminal Proteins in Mated Drosophila FemalesR37HD038921 · NICHD · CORNELL UNIVERSITY · PI Mariana Federica Wolfner · 2020 to 2026
$2.7M
A comparative population genomic approach for high-resolution inference of natural selection in fruit fliesF32GM135998 · NIGMS · STANFORD UNIVERSITY · PI KIM, BERNARD YOUNGSOO · 2020 to 2021
$131k
NIAID NIH HHS R01 AI095491NICHD NIH HHS R37 HD038921NIGMS NIH HHS F32 GM135998NIGMS NIH HHS R35 GM122592
6 · The paper itself

Abstract

Across internally fertilising species, males transfer ejaculate proteins that trigger wide-ranging changes in female behaviour and physiology. Much theory has been developed to explore the drivers of ejaculate protein evolution. The accelerating availability of high-quality genomes now allows us to test how these proteins are evolving at fine taxonomic scales. Here, we use genomes from 264 species to chart the evolutionary history of Sex Peptide (SP), a potent regulator of female post-mating responses in

Indexed as

Drosophila melanogasterDrosophila ProteinsAnimalsBiological EvolutionDrosophilaFemaleIntercellular Signaling Peptides and ProteinsMalePeptidesReceptors, PeptideReproductionSexual Behavior, AnimalDrosophila ProteinsIntercellular Signaling Peptides and ProteinsPeptidesReceptors, Peptidesex peptide receptor, DrosophilaSP protein, Drosophilacoevolutiongene family evolutionreproductionsexual conflictsexual selection

Identifiers

PMID38215185
PMCPMC10801855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.