Evidence map›Paper›PMID 38214931›Full record

ArticleJAMA network open2024

Adverse Safety Events in Emergency Medical Services Care of Children With Out-of-Hospital Cardiac Arrest.

Carl O Eriksson, Nathan Bahr, Garth Meckler, Matthew Hansen, Grace Walker-Stevenson, Ahamed Idris, Tom P Aufderheide, Mohamud R Daya, Ericka L Fink, Jonathan Jui and 7 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JAMA network open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07504211 (Augmenting the On-Scene Medic), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07504211 naactive not recruitingnot on this map

Augmenting the On-Scene Medic (ATOM): A Randomized, Controlled, Multicenter Study to Assess the Effectiveness of Augmented Reality Software on Prehospital Pediatric Medication Administration Accuracy

TypeinterventionalSponsorWestern Michigan University School of MedicineRan2023 to 2026Enrolled312ConditionsMedication Errors, Pediatric Medication ErrorArmsAugmented reality software for pediatric drug dosing
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 2 countries.

Carl O ErikssonDepartment of Pediatrics, Oregon Health and Science University, Portland.
Nathan BahrDepartment of Emergency Medicine, Oregon Health and Science University, Portland.
Garth MecklerDepartment of Pediatric Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Matthew HansenDepartment of Emergency Medicine, Oregon Health and Science University, Portland.
Grace Walker-StevensonPublic Health Division, Multnomah County Health Department, Portland, Oregon.
Ahamed IdrisDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas.
Tom P AufderheideDepartment of Emergency Medicine, Medical College of Wisconsin, Milwaukee.
Mohamud R DayaDepartment of Emergency Medicine, Oregon Health and Science University, Portland.
Ericka L FinkDepartment of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Jonathan JuiDepartment of Emergency Medicine, Oregon Health and Science University, Portland.
Maureen LuetjeDepartment of Emergency Medicine, Medical College of Wisconsin, Milwaukee.
Christian Martin-GillDepartment of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Steven McgaugheyDepartment of Emergency Medicine, Oregon Health and Science University, Portland.
Jon PelletierDepartment of Pediatrics, Akron's Children's Hospital, Akron, Ohio.
Danny ThomasDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee.
Jeanne-Marie GuiseDepartment of Obstetrics, Gynecology, and Reproductive Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Child Safety Initiative–Emergency Medical Services for Children
Oregon Health & Science University · USCenter for Children · USMedical College of Wisconsin · USAkron Children's Hospital · USBeth Israel Deaconess Medical Center · USMultnomah County Health Department · USThe University of Texas Southwestern Medical Center · USUniversity of British Columbia · CAUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Understanding and preventing adverse safety events in pediatric out-of-hospital cardiac arrestsR01HL141429 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI JEANNE-MARIE GUISE · 2018 to 2026
$6.0M
NHLBI NIH HHS R01 HL141429
6 · The paper itself

Abstract

Importance: Survival for children with out-of-hospital cardiac arrest (OHCA) remains poor despite improvements in adult OHCA survival. Objective: To characterize the frequency of and factors associated with adverse safety events (ASEs) in pediatric OHCA. Design, Setting, and Participants: This population-based retrospective cohort study examined patient care reports from 51 emergency medical services (EMS) agencies in California, Georgia, Oregon, Pennsylvania, Texas, and Wisconsin for children younger than 18 years with an OHCA in which resuscitation was attempted by EMS personnel between 2013 and 2019. Medical record review was conducted from January 2019 to April 2022 and data analysis from October 2022 to February 2023. Main Outcomes and Measure: Severe ASEs during the patient encounter (eg, failure to give an indicated medication, 10-fold medication overdose). Results: A total of 1019 encounters of EMS-treated pediatric OHCA were evaluated; 465 patients (46%) were younger than 12 months. At least 1 severe ASE occurred in 610 patients (60%), and 310 patients (30%) had 2 or more. Neonates had the highest frequency of ASEs. The most common severe ASEs involved epinephrine administration (332 [30%]), vascular access (212 [19%]), and ventilation (160 [14%]). In multivariable logistic regression, the only factor associated with severe ASEs was young age. Neonates with birth-related and non-birth-related OHCA had greater odds of a severe ASE compared with adolescents (birth-related: odds ratio [OR], 7.0; 95% CI, 3.1-16.1; non-birth-related: OR, 3.4; 95% CI, 1.2-9.6). Conclusions and Relevance: In this large geographically diverse cohort of children with EMS-treated OHCA, 60% of all patients experienced at least 1 severe ASE. The odds of a severe ASE were higher for neonates than adolescents and even higher when the cardiac arrest was birth related. Given the national increase in out-of-hospital births and ongoing poor outcomes of OHCA in young children, these findings represent an urgent call to action to improve care delivery and training for this population.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAdolescentAdultChildChild, PreschoolHumansInfant, NewbornOregonRetrospective Studies

Identifiers

PMID38214931
PMCPMC10787316
OpenAlexW4390793166

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.