Evidence map›Paper›PMID 38214528›Full record

ArticleJournal of bacteriology2024

BadR directly represses the expression of the glycerol utilization operon in the Lyme disease pathogen.

Jun-Jie Zhang, Sajith Raghunandanan, Qian Wang, Raj Priya, Fuad Alanazi, Yongliang Lou, X Frank Yang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Virulence Regulation inMicroorganisms · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Jun-Jie ZhangDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Sajith RaghunandananDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-4526-307X
Qian WangDepartment of Clinical Laboratory, Wenzhou People's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Raj PriyaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-9272-9207
Fuad AlanaziDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0009-0001-5328-6239
Yongliang LouWenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
X Frank YangDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-7231-3167
Indiana University School of MedicineWenzhou Medical University · CNKing Saud University · SA

Funding

Regulatory Network of the Lyme Disease PathogenR01AI083640 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI X. Frank Yang · 2009 to 2026
$5.9M
Targeting Cyclic Dinucleotide Signaling Pathways to Interrupt the Nature Cycle of Borrelia burgdorferiR01AI152235 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SINTIM, HERMAN O, YANG, X. FRANK · 2020 to 2024
$3.4M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015481 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FIFE, ROSE S · 2001 to 2001
$1.6M
NCRR NIH HHS C06 RR015481NIAID NIH HHS R01 AI083640NIAID NIH HHS R01 AI152235
6 · The paper itself

Abstract

Glycerol utilization as a carbohydrate source by

Indexed as

BorreliaBorrelia burgdorferiLyme DiseaseTicksAnimalsBacterial ProteinsGene Expression Regulation, BacterialGlycerolHost AdaptationMammalsOperonBacterial ProteinsGlycerolBorrelia burgdorferiglycerol metabolismLyme diseasetick

Identifiers

PMID38214528
PMCPMC10882987
OpenAlexW4390794224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.