Evidence map›Paper›PMID 38214510›Full record

ArticlemBio2024

Omar M Warsi, Lina M Upterworth, Annika Breidenstein, Ulrika Lustig, Kasper Mikkelsen, Tamás Nagy, Dávid Szatmari, Hanne Ingmer, Dan I Andersson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Omar M WarsiDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-3175-1184
Lina M UpterworthDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Germany.
Annika BreidensteinDepartment of Medical Chemistry and Biophysics, Umeå University, Umeå, Sweden.
Ulrika LustigDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Kasper MikkelsenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Tamás NagyDepartment of Laboratory Medicine, Medical School, University of Pécs, Pécs, Hungary.
Dávid SzatmariDepartment of Biophysics, Medical School, University of Pécs, Pécs, Hungary.
Hanne IngmerDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8350-5631
Dan I AnderssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-6640-2174
Uppsala University · SEUniversity of Copenhagen · DKUniversity of Pecs · HUChristian-Albrechts-Universität zu Kiel · DEUmeå University · SE

Funding

Svenska Forskningsrådet Formas (Formas) 2019-00425Vetenskapsrådet (VR) 2021-02091
6 · The paper itself

Abstract

Ionophores are antibacterial compounds that affect bacterial growth by changing intracellular concentrations of the essential cations, sodium and potassium. They are extensively used in animal husbandry to increase productivity and reduce infectious diseases, but our understanding of the potential for and effects of resistance development to ionophores is poorly known. Thus, given their widespread global usage, it is important to determine the potential negative consequences of ionophore use on human and animal health. In this study, we demonstrate that exposure to the ionophore monensin can select for resistant mutants in the human and animal pathogen

Indexed as

MonensinStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsHumansIonophoresMiceProteomicsPurinesStaphylococcus aureusVirulenceAnti-Bacterial AgentsIonophoresMonensinPurinescross-resistancedrug resistance evolutiondrug resistance mechanismsfitnessionophoremouse experimentpurine metabolism

Identifiers

PMID38214510
PMCPMC10865815
OpenAlexW4390795379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.