Evidence map›Paper›PMID 38214334›Full record

ArticleThe Laryngoscope2024

A Proof-of-Concept Computer Vision Approach for Measurement of Tympanic Membrane Perforations.

Obinna Nwosu, Krish Suresh, Renata Knoll, Daniel J Lee, Matthew G Crowson

Abstract read
In one paragraph

Article in The Laryngoscope, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Obinna NwosuDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, USA.ORCID 0000-0003-0886-1561
Krish SureshDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, USA.ORCID 0000-0001-7517-0280
Renata KnollDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, USA.
Daniel J LeeDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, USA.
Matthew G CrowsonDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, USA.ORCID 0000-0001-9950-0985

Funding

RESEARCH TRAINING IN OTOLARYNGOLOGYT32DC000020 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI JUNG, DAVID H, SIMONYAN, KRISTINA · 1990 to 2025
$2.4M
NIDCD NIH HHS T32 DC000020
6 · The paper itself

Abstract

objectiveSize, an important characteristic of a tympanic membrane perforation (TMP), is commonly assessed with gross estimation via visual inspection, a practice which is prone to inaccuracy. Herein, we demonstrate feasibility of a proof-of-concept computer vision model for estimating TMP size in a small set of perforations.

methodsAn open-source deep learning architecture was used to train a model to segment and calculate the area of a perforation and the visualized tympanic membrane (TM) in a set of endoscopic images of mostly anterior and relatively small TMPs. The model then computed relative TMP size by calculating the ratio of perforation area to TM area. Model performance on the test dataset was compared to ground-truth manual annotations. In a validation survey, otolaryngologists were tasked with estimating the size of TMPs from the test dataset. The primary outcome was the average absolute error of model size predictions and clinician estimates compared to sizes determined by ground-truth manual annotations.

resultsThe model's average absolute error for size predictions was a 0.8% overestimation for all test perforations. Conversely, among the 38 survey respondents, the average clinician error was a 11.0% overestimation (95% CI, 5.2-16.7%, p = 0.003).

conclusionsIn a small sample of TMPs, we demonstrated a computer vision approach for estimating TMP size is feasible. Further validation studies must be done with significantly larger and more heterogenous datasets. LEVEL OF EVIDENCE: N/A Laryngoscope, 134:2906-2911, 2024.

Indexed as

Tympanic Membrane PerforationDeep LearningEndoscopyFeasibility StudiesHumansMaleProof of Concept StudyTympanic Membranecomputer visionmachine learningtympanic membrane perforation size

Identifiers

PMID38214334
PMCPMC12199715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.