SynthesisJournal of the American Heart Association2024
Intravascular Imaging-Guided Versus Angiography-Guided Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis of Randomized Trials.
Synthesis in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Intravascular imaging-guided versus angiography-guided percutaneous coronary intervention in multivessel coronary artery disease: a systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials.BMC cardiovascular disorders · 2026Pooled it
- IVUS-Guided Versus Angiography-Guided PCI for Unprotected Left Main Coronary Artery Disease: A Systematic Review, Meta-Analysis, and GRADE Assessment of Randomized Trials.Clinical cardiology · 2026Pooled it
- Pooled it
- A Systematic Review on the Use of Intravascular Ultrasound and Optical Coherence Tomography During Femoropopliteal Endovascular Intervention.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Pooled it
- Impact of percutaneous coronary intervention with different guidance modalities in patients with coronary artery lesions: a network meta-analysis and systematic review.Frontiers in cardiovascular medicine · 2025Pooled it
- Intravascular imaging-guided versus angiography-guided percutaneous coronary intervention: a systematic review and bayesian network meta-analysis of randomized controlled trials.BMC cardiovascular disorders · 2024Pooled it
- Quality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial.The American journal of cardiology · 2024Trial
- Intracoronary imaging in percutaneous coronary intervention: why, when, how and which from large, randomized trials.Nature reviews. Cardiology · 2026Review
- Survival and Health Status Outcomes Following IVUS-Guided Stent Optimization: A Real-World Registry.JACC. Asia · 2026Article
- Intravascular Imaging Versus Physiology Assessment for Intermediate Lesions During PCI.Biomedicines · 2026Review
- Assessment of Optimal Stent Implantation with the Use of Optical Coherence Tomography in Patients with Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2026Article
- Intravascular Imaging-Guided Percutaneous Coronary Intervention: A Critical Appraisal of Evidence and Clinical Practice : Short title:Intravascular Imaging-Guided Percutaneous Coronary Intervention.Galen medical journal · 2026Review
- Comparative effectiveness and outcomes of physiology- and imaging-guided PCI: an evidence synthesis and network meta-analysis of FFR, iFR, OCT, and IVUS.Frontiers in cardiovascular medicine · 2026Review
- Accuracy of artificial intelligence in meta-analysis: A comparative study of ChatGPT 4.0 and traditional methods in data synthesis.World journal of methodology · 2025Article
- Acute Coronary Syndromes: State-of-the-Art Diagnosis, Management, and Secondary Prevention.Journal of clinical medicine · 2025Review
- Guideline for Chronic Coronary Syndrome - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Cost-Utility Analysis of Different Treatment Modalities in Patients Undergoing Percutaneous Coronary Intervention: Thai PCI Registry.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- When Functional Assessment Meets Intravascular Imaging in Patients with Coronary Artery Disease.Journal of cardiovascular development and disease · 2025Review
- Optical Coherence Tomography-Guided vs. Angiography-Guided Percutaneous Coronary Intervention for Complex Coronary Lesions: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2025Review
- Latest Evidence on Intravascular Imaging: A Literature Review.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
backgroundDespite the initial evidence supporting the utility of intravascular imaging to guide percutaneous coronary intervention (PCI), adoption remains low. Recent new trial data have become available. An updated study-level meta-analysis comparing intravascular imaging to angiography to guide PCI was performed. This study aimed to evaluate the clinical outcomes of intravascular imaging-guided PCI compared with angiography-guided PCI. METHODS AND
resultsA random-effects meta-analysis was performed on the basis of the intention-to-treat principle. The primary outcomes were major adverse cardiac events, cardiac death, and all-cause death. Mixed-effects meta-regression was performed to investigate the impact of complex PCI on the primary outcomes. A total of 16 trials with 7814 patients were included. The weighted mean follow-up duration was 28.8 months. Intravascular imaging led to a lower risk of major adverse cardiac events (relative risk [RR], 0.67 [95% CI, 0.55-0.82];
conclusionsIn patients undergoing PCI, intravascular imaging is associated with reductions in major adverse cardiac events, cardiac death, stent thrombosis, target-lesion revascularization, and target-vessel revascularization. The magnitude of benefit is large and consistent across all included studies. There may also be benefits in all-cause death, particularly in complex lesion subsets. These results support the use of intravascular imaging as standard of care and updates of clinical guidelines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.