Evidence map›Paper›PMID 38214192›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2024

A practical guide to real-world implementation of pre-emptive therapy for Cytomegalovirus disease prevention in high-risk seronegative liver transplant recipients with seropositive donors.

Madeleine R Heldman, Bailey Dunn, Evan Clemens, Megan Henderson, Cynthia E Fisher, Robert M Rakita, Catherine E Kling, Ajit P Limaye

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Current and Future Strategies for the Prevention and Treatment of Cytomegalovirus Infections in Transplantation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Review
  2. Cytomegalovirus Reactivation Is Associated With Lower Rates of Hepatocellular Carcinoma Recurrence After Liver Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Madeleine R HeldmanDivision of Infectious Diseases, Department of Medicine, Duke University, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-9424-1870
Bailey DunnDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Evan ClemensDepartment of Pharmacy, University of Washington, Seattle, Washington, USA.
Megan HendersonDepartment of Pharmacy, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-2662-452X
Cynthia E FisherDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-6661-9162
Robert M RakitaDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8105-8455
Catherine E KlingDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Ajit P LimayeDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-5350-9025
University of Washington · USDuke University · US

Funding

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)U01AI163090 · NIAID · UNIVERSITY OF WASHINGTON · PI Don J Diamond, Cynthia E Fisher · 2021 to 2026
$17.4M
Respiratory Viral Determinants of Chronic Lung Allograft DysfunctionK23HL143050 · NHLBI · UNIVERSITY OF WASHINGTON · PI FISHER, CYNTHIA E · 2018 to 2022
$986k
National Institute of Allergy and Infectious Diseases AI16390NHLBI NIH HHS K23 HL143050NIAID NIH HHS U01 AI163090
6 · The paper itself

Abstract

The Comparison of Antiviral Preventative Strategies In Liver Transplant (CAPSIL) study showed pre-emptive therapy (PET) to be superior to antiviral prophylaxis for Cytomegalovirus (CMV) disease prevention in high-risk CMV seronegative liver transplant recipients (LTRs) with seropositive donors (D

Indexed as

Antiviral AgentsCytomegalovirusCytomegalovirus InfectionsLiver TransplantationTissue DonorsHumansTransplant RecipientsViremiaAntiviral AgentsCytomegalovirusliver transplantationpre‐emptive therapyquality improvementvalganciclovir

Identifiers

PMID38214192
PMCPMC11187685
OpenAlexW4390789553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.