Evidence map›Paper›PMID 38214012›Full record

ArticleAutophagy reports2023

Atg8 family proteins, LIR/AIM motifs and other interaction modes.

Vladimir V Rogov, Ioannis P Nezis, Panagiotis Tsapras, Hong Zhang, Yasin Dagdas, Nobuo N Noda, Hitoshi Nakatogawa, Martina Wirth, Stephane Mouilleron, David G McEwan and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Autophagy reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
19.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 91 citations in OpenAlex.

  1. PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators.Journal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Regulation and roles of mammalian mitophagy.Nature reviews. Molecular cell biology · 2026
    Review
  12. Article
  13. MinimalRSC chemical biology · 2026
    Article
  14. Autophagy · 2026
    Review
  15. The Human Autophagy Core Complexes.Annual review of biochemistry · 2026
    Review
  16. Article
  17. MAVISp: A modular structure-based framework for protein variant effects.Protein science : a publication of the Protein Society · 2026
    Article
  18. Article
  19. Review
  20. Autophagy · 2026
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 8 countries.

Vladimir V RogovInstitute for Pharmaceutical Chemistry, Department of Biochemistry, Chemistry and Pharmacy, Goethe University, 60438 Frankfurt, am Main, and Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe University, 60438 Frankfurt am Main, Germany.
Ioannis P NezisSchool of Life Sciences, University of Warwick, CV4 7AL Coventry, UK.
Panagiotis TsaprasSchool of Life Sciences, University of Warwick, CV4 7AL Coventry, UK.
Hong ZhangNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China and College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Yasin DagdasGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Nobuo N NodaInstitute for Genetic Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo 060-0815, Japan.
Hitoshi NakatogawaSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Martina WirthMolecular Cell Biology of Autophagy, The Francis Crick Institute, London, UK.
Stephane MouilleronStructural Biology Science Technology Platform, The Francis Crick Institute, London, UK.
David G McEwanCancer Research UK Beatson Institute, Glasgow, UK.
Christian BehrendsMunich Cluster of Systems Neurology, Ludwig-Maximilians-Universität München, München, Germany.
Vojo DereticAutophagy, Inflammation and Metabolism Center of Biochemical Research Excellence, Albuquerque, NM and Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM.
Zvulun ElazarDepartment of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.
Sharon A ToozeMolecular Cell Biology of Autophagy, The Francis Crick Institute, London, UK.
Ivan DikicInstitute of Biochemistry II, Medical Faculty, Goethe-University, Frankfurt am Main, and Buchmann Institute for Molecular Life Sciences, Frankfurt am Main, Germany.
Trond LamarkAutophagy Research Group, Department of Medical Biology, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.
Terje JohansenAutophagy Research Group, Department of Medical Biology, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.ORCID 0000-0003-1451-9578
The Francis Crick Institute · GBGoethe University Frankfurt · DEUiT The Arctic University of Norway · NOUniversity of Warwick · GBCancer Research UK Scotland Institute · GBGregor Mendel Institute of Molecular Plant Biology · ATHokkaido University · JPInstitute of Biophysics · CNMunich Cluster for Systems Neurology · DETokyo Institute of Technology · JPUniversity of New Mexico · USWeizmann Institute of Science · IL

Funding

Wellcome Trust FC001187Wellcome Trust FC001999
6 · The paper itself

Abstract

The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes involving vesicle fusion and transport where the lysosome/vacuole is the end station. Nuclear roles of Atg8 proteins are also emerging. Here, we review the structural and functional features of Atg8 family proteins and their protein-protein interaction modes in model organisms such as yeast,

Indexed as

AIMAtg8AutophagyLDSLIRphosphorylationprotein-protein interactionUDS

Identifiers

PMID38214012
PMCPMC7615515
OpenAlexW4327980509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.