ArticleOrthopedic & muscular system : current research2023
Long Duration Ultrasound Combined with Platelet-Rich Plasma Injection for Return to Sport after Soft Tissue Injury: A Single Center Study.
Article in Orthopedic & muscular system : current research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Regenerative Trifecta: A Multimodal Regenerative Approach to Soft Tissue Injury Recovery and Return to Sport.Cureus · 2026Review
- Impact of Adequate Disinfection Techniques for Ultrasound-Guided Injections in Musculoskeletal Rehabilitation: A Scoping Review.Diagnostics (Basel, Switzerland) · 2025Review
- Clinical Uses Of Long-Duration Ultrasound And Long-Duration Sonophoresis In Sports Medicine - Minireview.Journal of orthopaedics (Chesterton, Ind.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Objective: The use of Long-Duration Ultrasound (LDU) and Platelet-Rich Plasma (PRP) treatments to facilitate injury healing and pain relief are typically utilized independently in sports medicine. Our study aimed to investigate the combined regenerative effect of daily LDU with high-concentration single-injection PRP for treating sport-related musculoskeletal injuries. Methods: In total, thirty-five competitive athletes (n=35) with grade II sprains and strains and tendinopathies injured during sport and unable to continue to play were sequentially administered PRP (n=20, 20.4 yoa, 18 male, 2 female) or PRP+LDU (n=15, 20.27 yoa, 14 male, 1 female). In the PRP treatment group, each subject was treated with a single injection of PRP consisting of 1.28 billion platelets/mL under ultrasound-image guidance to the injury site. The PRP+LDU treatment group received the same PRP injection procedure with a 14-day, 4 hr per day, 18,720 J ultrasound treatment applied over the injection site. The Numeric Ration pain Scale (NRS, 0-10), Range of Motion (ROM, 0-100%), Clinical Strength numeric score (CS, 0-5), and time of injury to return to sport (days) were measured at baseline and Return to Play (RTP). The global health improvement score (GROC -7 to +7) was measured upon RTP. Results: All patients completed rehabilitation and returned to the sport after debilitating injuries. PRP+LDU returned athletes to play 21.33 days quicker (p<0.0001), decreased injury pain by 0.88 NRS points (p=0.0086), and improved patient global health by 1.28 points GROC (p<0.0001) over PRP treatment alone (95% Confidence interval, 11.26 to 31.40 days faster). There were no significant differences in strength (p=0.498) or range of motion (p=0.8581) improvement between PRP and PRP+LDU at the RTP or baseline patient demographic variables. Conclusion: Adding LDU at-home treatment to PRP injection therapy significantly reduces the time to return to sport, increases pain reduction, and improves overall health for patients recovering from sport-related injury. The daily LDU treatment facilitates and enhances regenerative medicine therapies such as PRP.
Indexed as
Identifiers
38213829PMC10783208W4390794421What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.