Evidence map›Paper›PMID 38213720›Full record

ArticleJournal of Cancer2024

Exploring the therapeutic potential of edible vegetables, fruits, and spices against cancer in various cell lines.

Md Rahmat Ali, A S M Ali Reza, Md Anwarul Haque, Md Jannatul Islam, Md Rezwan Hossain, Md Ibrahim Mollah, Md Badrul Islam, Joy Sarker, Mamunur Rashid, Md Golam Sadik and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review.Indian journal of clinical biochemistry : IJCB · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Md Rahmat AliDepartment of Pharmacy, University of Rajshahi, Bangladesh.
A S M Ali RezaDepartment of Pharmacy, International Islamic University Chittagong, Bangladesh.
Md Anwarul HaqueDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Md Jannatul IslamDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Md Rezwan HossainDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Md Ibrahim MollahDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Md Badrul IslamBangladesh Council of Scientific and Industrial Research (BCSIR), Rajshahi, Bangladesh.
Joy SarkerDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Mamunur RashidDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Md Golam SadikDepartment of Pharmacy, University of Rajshahi, Bangladesh.
Donatella CiciaDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Raffaele CapassoDepartment of Agricultural Sciences, University of Naples Federico II, Italy.
Mohsin KaziDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457; Riyadh 11451, Saudi Arabia.
Ahm Khurshid AlamDepartment of Pharmacy, University of Rajshahi, Bangladesh.
University of Rajshahi · BDFederico II University Hospital · ITBangladesh Council of Scientific and Industrial Research · BDInternational Islamic University Chittagong · BDKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is rapidly becoming the leading cause of death globally. This study aimed to identify edible foods with cytotoxic and/or antioxidant activities that can prevent cancer when consumed in a regular diet. Sixty-eight edible foods were purchased from the local market, and the materials were extracted with 80% methanol. The cytotoxic activity of the extracts was evaluated using MTT on HeLa, H2228, HEK293, and H3122 cell lines. To study apoptosis, triple fluorescence labeling with DAPI, Annexin V, and propidium iodide was used. The phenolic content, antioxidant capacity, and free radical scavenging capabilities were studied using conventional spectrophotometric techniques. Among the edible foods, carrot, pointed gourd, wax gourd, ficus, apple, lemon, cumin seed, and white peppercorn showed moderate cytotoxicity in HeLa cells. The growth of HeLa cells was significantly inhibited dose-dependently by tomato, banana, Indian spinach, guava, lemon peel, and coriander (IC

Indexed as

Anticancer activityAntioxidantsApoptosisCancerFree radicalsFruitsSpicesVegetables

Identifiers

PMID38213720
PMCPMC10777031
OpenAlexW4389340262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.