Evidence map›Paper›PMID 38213597›Full record

ArticleHeliyon2023

Effect of acupuncture therapy on vaccine-induced immune response in d-galactose-induced aging rats.

Jia Li, Fangyuan Liang, Ling Xiao, Wei Lu, Hua Wang

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jia LiCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China.
Fangyuan LiangCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China.
Ling XiaoSchool of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan 430061, China.
Wei LuClinical College of Chinese Medicine, Hubei University of Chinese Medicine, Wuhan 430061, China.
Hua WangCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China.
Hubei University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore whether acupuncture and moxibustion can enhance the immune response by increasing the expression of the endogenous adjuvant HSP70 mRNA. Method: Forty Wistar rats were divided into four groups: model immune acupuncture group (A), model immune control group (B), normal immune acupuncture group (C), and normal immune control group (D). Model immune groups A and B were induced by injecting d-galactose for 6 weeks. Rats in groups A and C were then treated with low-frequency electroacupuncture (EA) at Zusanli (ST36), Guanyuan (CV4), and Baihui (GV20) and moxibustion for 3 weeks. Subsequently, all rats were observed for 2 more weeks. At the 12th week, diphtheria antitoxin titers were determined using the Vero cell trace neutralization method, CD4 Results: Compared with the normal immune control, the diphtheria antitoxin titer, CD4 Conclusion: Acupuncture and moxibustion may enhance the humoral immune response (diphtheria antitoxin titer) and cellular immune response (peripheral blood CD4

Indexed as

AcupunctureAdjuvantHSP70 mRNAImmune response

Identifiers

PMID38213597
PMCPMC10782161
OpenAlexW4388802087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.