Evidence map›Paper›PMID 38213432›Full record

ArticleSurgical neurology international2023

Chitosan/PEG-mediated spinal cord fusion after complete dorsal transection in rabbits - functional results at 30 days.

Michael Lebenstein-Gumovski, Tanzila Rasueva, Alexander Zharchenko, Robert Bashahanov, Dmitry A Kovalev, Andrey Zhirov, Anton Shatokhin, Andrey Grin

Open access · hybridAbstract read
In one paragraph

Article in Surgical neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. [Establishment of a canine model of vascularized allogeneic spinal cord transplantation and preliminary study on spinal cord continuity reconstruction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael Lebenstein-GumovskiDepartment of Neurology and Neurosurgery, Stavropol State Medical University, Stavropol, Russian Federation.
Tanzila RasuevaClinic of Neurosurgery, N. V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department, Moscow, Russian Federation.
Alexander ZharchenkoDepartment of General Medicine, Stavropol State Medical University, Stavropol, Russian Federation.
Robert BashahanovDepartment of General Medicine, Stavropol State Medical University, Stavropol, Russian Federation.
Dmitry A KovalevLaboratory of Biochemistry, Stavropol Research Institute for Plague Control, Stavropol, Russian Federation.
Andrey ZhirovLaboratory of Biochemistry, Stavropol Research Institute for Plague Control, Stavropol, Russian Federation.
Anton ShatokhinDepartment of Neurology and Neurosurgery, Stavropol State Medical University, Stavropol, Russian Federation.
Andrey GrinClinic of Neurosurgery, N. V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department, Moscow, Russian Federation.
Stavropol State Medical University · RUResearch Institute of Emergency Care · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim was to study functional recovery in experimental animals (rabbits) with transected spinal cords treated with a combination of photo-cross-linked chitosan in a homogeneous mixture with polyethylene glycol (PEG-chitosan). Methods: 20 rabbits ( Results: In the experimental group, partial recovery of movements, sensory function, and sphincter control were all observed by postoperative day 30. Paraplegia and anesthesia persisted in the control group; 4 controls died versus none in the test group. Conclusion: PEG-chitosan is a candidate for neurological restoration after spinal paralysis.

Indexed as

ChitosanNeuroPEGPEGPEG-chitosanPolyethylene glycolSpinal cord injurySpinal injury

Identifiers

PMID38213432
PMCPMC10783696
OpenAlexW4389741718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.