Evidence map›Paper›PMID 38213419›Full record

ArticleCritical care explorations2024

The Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal Compared With Conventional Lung Protective Ventilation on Cardiac Function.

Peter J McGuigan, Emma M Bowcock, Nicholas A Barrett, Bronagh Blackwood, Andrew J Boyle, Andrew J Cadamy, Luigi Camporota, John Conlon, Matthew E Cove, Michael A Gillies and 10 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Extracorporeal COAnnals of intensive care · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 3 countries.

Peter J McGuiganRoyal Victoria Hospital, Belfast, United Kingdom.
Emma M BowcockNepean Hospital, Sydney, Australia.
Nicholas A BarrettGuy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Bronagh BlackwoodWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.
Andrew J BoyleRoyal Victoria Hospital, Belfast, United Kingdom.
Andrew J CadamyQueen Elizabeth University Hospital, Glasgow, United Kingdom.
Luigi CamporotaGuy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
John ConlonWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.
Matthew E CoveNational University Hospital, Singapore, Singapore.
Michael A GilliesEdinburgh Royal Infirmary, Edinburgh, United Kingdom.
Clíona McDowellNorthern Ireland Clinical Trials Unit, Belfast, United Kingdom.
James J McNameeRoyal Victoria Hospital, Belfast, United Kingdom.
Cecilia M O'KaneWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.
Alex PuxtyGlasgow Royal Infirmary, Glasgow, United Kingdom.
Malcolm SimQueen Elizabeth University Hospital, Glasgow, United Kingdom.
Rebecca Parsons-SimmondsUniversity Hospital of Wales, Cardiff, United Kingdom.
Tamas SzakmanyRoyal Gwent Hospital, Aneurin Bevan University Health Board, Newport, United Kingdom.
Neil YoungEdinburgh Royal Infirmary, Edinburgh, United Kingdom.
Sam OrdeNepean Hospital, Sydney, Australia.
Daniel F McAuleyRoyal Victoria Hospital, Belfast, United Kingdom.
Queen's University Belfast · GBEdinburgh Royal Infirmary · GBKing's College London · GBQueen Elizabeth University Hospital · GBUniversity of Sydney · AUGlasgow Royal Infirmary · GBNational University Hospital · SGRoyal Gwent Hospital · GBRoyal Victoria Hospital · GBUniversity Hospital of Wales · GBUniversity of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLower tidal volume ventilation (targeting 3 mL/kg predicted body weight, PBW) facilitated by extracorporeal carbon dioxide removal (ECCO

designSubstudy of the REST trial.

settingNine U.K. ICUs. PATIENTS: Patients with AHRF (Pao

interventionTransthoracic echocardiography and N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements were collected at baseline and postrandomization in patients randomized to ECCO MEASUREMENTS: The primary outcome measures were a difference in tricuspid annular plane systolic excursion (TAPSE) on postrandomization echocardiogram and difference in NT-proBNP postrandomization.

resultsThere were 21 patients included in the echocardiography cohort (ECCO

conclusionsIn patients with AHRF, a reduction in tidal volume facilitated by ECCO

Indexed as

acute hypoxemic respiratory failureechocardiographyextracorporeal circulationN-terminal pro-B-type natriuretic peptideright ventricle

Identifiers

PMID38213419
PMCPMC10783412
OpenAlexW4390691620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.