Evidence map›Paper›PMID 38213319›Full record

ArticleDiseases & research2023

Secretome of Dental Pulp-Derived Stem Cells Reduces Inflammation and Proliferation of Glioblastoma Cells by Deactivating Mapk-Akt Pathway.

Prateeksha Prateeksha, Md Sariful Islam Howlader, Surajit Hansda, Prathyusha Naidu, Manjusri Das, Faten Abo-Aziza, Hiranmoy Das

Abstract read
In one paragraph

Article in Diseases & research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Human dental pulp stem cells for spinal cord injury.Stem cell research & therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prateeksha PrateekshaDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Md Sariful Islam HowladerDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Surajit HansdaDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Prathyusha NaiduDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Manjusri DasDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Faten Abo-AzizaDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.
Hiranmoy DasDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA.

Funding

Myeloid KLF2 regulation mechanisms in rheumatoid arthritisR01AR068279 · NIAMS · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI DAS, HIRANMOY · 2016 to 2022
$1.7M
Regenerative Therapy for Corneal Endothelial Dystrophies and InjuriesR42EY031196 · NEI · RASHMIVU, LLC · PI DAS, HIRANMOY · 2020 to 2020
$300k
Nanofiber Expanded CD34+ Stem Cells for Osteoporosis TherapyR41AG057242 · NIA · HNB THERAPEUTICS, LLC · PI DAS, HIRANMOY · 2018 to 2018
$225k
NEI NIH HHS R42 EY031196NIAMS NIH HHS R01 AR068279NIA NIH HHS R41 AG057242
6 · The paper itself

Abstract

Background: Dental pulp-derived stem cells (DPSC) is a promising therapy as they modulate the immune response, so we evaluated the inhibitory effect of DPSC secretome (DPSC Methods: The U87-MG cells were cultured with DPSC Results: DPSC Conclusion: Our findings lend the first evidence of the inhibitory effects of DPSC

Indexed as

Cell cycleCellular bioenergeticsDental pulp-derived stem cells secretomeInflammationP38 MAPK-AKT pathway

Identifiers

PMID38213319
PMCPMC10783424

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.