Evidence map›Paper›PMID 38213255›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Efficacy and safety of Chinese herbal medicine as adjunctive therapy in sepsis patients with bloodstream infection: a propensity-matched analysis.

Zhou Xianshi, Zhong Minlin, X I Xiaotu, L I Jun, Tang Guanghua

Open access · greenAbstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhou Xianshithe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Zhong MinlinEmergency Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
X I XiaotuEmergency Department, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
L I JunAdministration Department, the First Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Tang Guanghuathe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Guangdong Provincial Hospital of Traditional Chinese Medicine · CNKey Laboratory of Guangdong Province · CN

Funding

Clinical Research Program of Guangdong Provincial Hospital of Chinese Medicine: Exploring the Epidemiological Characteristics and Screening Key Prognostic Indicators of Sepsis Patients with Bloodstream Infection 2019KT1317which is a sub-project of Guangdong Provincial Key Laboratory of Research on Emergency in TCM 2017B030314176
6 · The paper itself

Abstract

objectiveTo investigate the efficacy and safety of Chinese herbal medicine in treating sepsis patients with bloodstream infection.

methodsA 6-year retrospective study was carried out at a university hospital in China. Adult sepsis patients with bloodstream infection were included. The primary outcome was 28-day mortality after admission. Propensity score method was used to adjust for possible confounding. 28-day mortality was estimated by Kaplan-Meier analysis and compared using the log-rank test. Cox regression analysis was carried out to identify factors impacting in-hospital mortality outcomes.

resultsFollowing the application of the propensity score method, a total of 176 patients were included. The all-cause 28-day mortality in the control group and Chinese herbal medicine group was 21.6% and 14.8%, respectively. Kaplan-Meier survival analysis showed that Chinese herbal medicine was associated with a lower hazard ratio (

conclusionsChinese herbal medicine, especially the blood-activating and stasis-eliminating herb, might have certain efficacy and safety in treating sepsis patients with bloodstream infection. Clinicians should prescribe blood-activating and stasis-eliminating herb in treating these two coalescent critical diseases as long as no contraindications exist. However, further studies are needed to validate our results.

Indexed as

Drugs, Chinese HerbalSepsisAdultHumansMedicine, Chinese TraditionalProportional Hazards ModelsRetrospective StudiesDrugs, Chinese Herbalbacteremiaherbal medicinemedicine, Chinese traditionalpropensity-matched analysissepsis

Identifiers

PMID38213255
PMCPMC10774732
OpenAlexW4390791394

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.