Evidence map›Paper›PMID 38213254›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Differences in vascular endothelial function and serum proteome between obese people with phlegm-dampness constitution and balanced constitution.

Zhu Linghui, Sun Ziwei, Guan Yuanyuan, Liu Meiyi, Zheng Yi, Y U Ruoxi, Wang Qi, L I Lingru

Open access · greenAbstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhu LinghuiSchool of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China.
Sun ZiweiNational Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Guan YuanyuanSchool of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China.
Liu MeiyiSchool of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China.
Zheng YiSchool of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China.
Y U RuoxiNational Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Wang QiNational Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
L I LingruNational Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Beijing University of Chinese Medicine · CN

Funding

General Program of National Natural Science of China: Qigui Slimming Prescription Upgrades the Activating Ability of the Phlegm-Dampness Constitution to Improve Obesity by Regulating the Thermogenesis Axis of Clostridium Enterica-Phytosphingosine-SphK/S1P-Ca Cycle 82374308National Key Research and Development Program: Development of Dietary Intervention Series for the Elderly with Decreased Functionality 2022YFC2010104National Nonprofit Institute Research Grant for Institute of Basic Theory for Chinese Medicine, CACMS: Methylation of Gut Microbiota-Host DNA Reveals the Mechanism of Promoting Phlegm-Dampness Constitution to Prevent Metabolic Diseases YZ-202151
6 · The paper itself

Abstract

objectiveTo evaluate the extent of vascular endothelial dysfunction and preliminary identify serum protein biomarkers associated with obese individuals at risk for cardiovascular disease (CVD).

methodsFifteen obese volunteers with the phlegm-dampness constitution or balanced constitution were recruited for this study respectively. The clinical baseline data was collected, and the vascular endothelial function was evaluated using the EndoPAT

resultsThere were no statistical differences found in the baseline data. For vascular endothelial function, the reactive hyperemia index (RHI) of the phlegm-dampness constitution obese group was significantly lower than that of the balanced constitution obese group (1.46 ± 0.30

conclusionVascular endothelial dysfunction was present in the phlegm-dampness constitution obese group. Thus, alterations in the expression levels of key serum proteins, including ApoA2, ACE-2, IL-33, and FoxP3 could serve as potential biomarkers in the obese population at risk of CVD.

Indexed as

Cardiovascular DiseasesMedicine, Chinese TraditionalBiomarkersBlood ProteinsForkhead Transcription FactorsHumansInterleukin-33ObesityProteomeBiomarkersBlood ProteinsForkhead Transcription FactorsInterleukin-33Proteomeobesityphlegm-dampness constitutionproteomereactive hyperemia indexvascular endothelial function

Identifiers

PMID38213254
PMCPMC10774723
OpenAlexW4390794239

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.