Evidence map›Paper›PMID 38213251›Full record

Trial reportJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Efficacy of Zhumian Tang formula granules combined with eszopiclone for the treatment of poor sleep quality: a multi-center, randomized controlled, superiority trial.

Wang Yichen, W U Shiyi, Wang Zhengyan, Chang Wenling, Xie Zhihao, Tang Xing, Zhao Songmei, Zhou Jing, Chen Zehong, Wang Chao and 1 more

Open access · greenAbstract readRandomized Controlled TrialMulticenter StudyEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Wang YichenOrthopedic geriatrics department, Sichuan Province Orthopedic Hospital, Chengdu 610093, China.
W U ShiyiDepartment of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Wang ZhengyanSub-health department, Sichuan Integrative Medicine Hospital, Chengdu 610041, China.
Chang WenlingDepartment of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Xie ZhihaoDepartment of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Tang XingCollege of Acupuncture and Massage, Chengdu University of Traditional Chinese Medicine, Chengdu 610041, China.
Zhao SongmeiInternal Medicine Department, Ya'an Hospital of Traditional Chinese Medicine, Ya'an 625000, China.
Zhou JingPreventive Treatment of Disease Center, Dazhou Integrated TCM and Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou 635000, China.
Chen ZehongGeriatrics Department, Dayi Wang Country Hospital of Traditional Chinese Medicine, Chengdu 611330, China.
Wang ChaoSub-health department, Sichuan Integrative Medicine Hospital, Chengdu 610041, China.
Yang ChunxiaDepartment of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
West China Medical Center of Sichuan University · CN

Funding

Natural Science Foundation of Sichuan Province: Study on the Efficacy and Mechanism of Acupuncture in Treating Drug-dependent Insomnia from the Liver based on Multi-modal fMRI Technology 2022NSFSC0858Sichuan Province Central Guided Local Science and Technology Development Special Project: a Study of the Chinese and Western Medicine Clinical Consensus Program for People with Poor Sleep Quality 2021ZYD0109
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of Zhumian Tang formula granules combined with eszopiclone for treating poor sleep quality.

methodsThis multi-center, dynamic block-randomized, parallel-group superiority clinical trial included 130 patients. The combined treatment group received Zhumian Tang formula granules combined with eszopiclone treatment, and the control group received eszopiclone treatment only. The group allocation ratio was 1∶1. The duration of treatment was 2 weeks. Participants were asked to complete questionnaires before treatment, after 1 week of the intervention, after 2 weeks of the intervention, and at the follow-up on week 3. The primary outcomes were the Pittsburgh Sleep Quality Index (PSQI) score and the total effective rate of treatment. The secondary outcome was the rate of adverse effects.

resultsCompared with the eszopiclone treatment group, the PSQI score of the combined treatment group was significantly lower after 2 weeks of the intervention (6.98

conclusionThe combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone. Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia.

Indexed as

Sleep Initiation and Maintenance DisordersDouble-Blind MethodEszopicloneHumansHypnotics and SedativesSleep QualityTreatment OutcomeEszopicloneHypnotics and Sedativeseszopiclonerandomized controlled trialsleep qualitysuperiorityZhumian Tang formula granules

Identifiers

PMID38213251
PMCPMC10774717
OpenAlexW4390795886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.