Evidence map›Paper›PMID 38213181›Full record

ArticleThe Analyst2024

Multiplexed electrical detection of whole viruses from plasma in a microfluidic platform.

Aaron Jankelow, Chih-Lin Chen, Thomas W Cowell, Javier Espinosa de Los Monteros, Zheng Bian, Victoria Kindratenko, Katherine Koprowski, Sriya Darsi, Hee-Sun Han, Enrique Valera and 1 more

Abstract read
In one paragraph

Article in The Analyst, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aaron JankelowDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.ORCID http://orcid.org/0000-0002-8329-3560
Chih-Lin ChenDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Thomas W CowellDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Javier Espinosa de Los MonterosDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.
Zheng BianDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.
Victoria KindratenkoDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.
Katherine KoprowskiDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.
Sriya DarsiDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.
Hee-Sun HanDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.ORCID http://orcid.org/0000-0003-3616-291X
Enrique ValeraDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.ORCID http://orcid.org/0000-0003-1359-6619
Rashid BashirDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. evalerac@illinois.edu.ORCID http://orcid.org/0000-0002-7225-9180

Funding

Point-of-Care Microfluidic Biochip for Biomarkers Monitoring for Contributing in Early Sepsis DiagnosisR01AI148385 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID · 2021 to 2024
$2.1M
NIAID NIH HHS R01 AI148385
6 · The paper itself

Abstract

The advancement of point-of-care diagnostics is crucial to improving patient outcomes, especially in areas with low access to hospitals or specialized laboratories. In particular, rapid, sensitive, and multiplexed detection of disease biomarkers has great potential to achieve accurate diagnosis and inform high quality care for patients. Our Coulter counting and immunocapture based detection system has previously shown its broad applicability in the detection of cells, proteins, and nucleic acids. This paper expands the capability of the platform by demonstrating multiplexed detection of whole-virus particles using electrically distinguishable hydrogel beads by demonstrating the capability of our platform to achieve simultaneous detection at clinically relevant concentrations of hepatitis A virus (>2 × 10

Indexed as

Nucleic AcidsParvovirus B19, HumanHumansMicrofluidicsProteinsNucleic AcidsProteins

Identifiers

PMID38213181
PMCPMC11646553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.