Evidence map›Paper›PMID 38213176›Full record

ReviewCurrent medicinal chemistry2024

A Comprehensive Review on the State of the Art of Breast Cancers in Italy.

Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Camillo Rosano, Annaluisa Mariconda, Federica Giuzio, Daniela Bonofiglio, Carmela Saturnino, Pasquale Longo, Maria Stefania Sinicropi

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Progression-free survival prediction and comparative metastasis detection accuracy ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Domenico IacopettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, Arcavacata di Rende, 87036, Italy.
Jessica CeramellaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, Arcavacata di Rende, 87036, Italy.
Alessia CatalanoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", Bari, 70126, Italy.
Camillo RosanoU.O. Proteomica e Spettrometria di Massa, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, Genova, 16132, Italy.
Annaluisa MaricondaDepartment of Science, University of Basilicata, Viale dell'Ateneo Lucano 10, Potenza, 85100, Italy.
Federica GiuzioDepartment of Science, University of Basilicata, Viale dell'Ateneo Lucano 10, Potenza, 85100, Italy.
Daniela BonofiglioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, Arcavacata di Rende, 87036, Italy.
Carmela SaturninoDepartment of Science, University of Basilicata, Viale dell'Ateneo Lucano 10, Potenza, 85100, Italy.
Pasquale LongoDepartment of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, 84084, Italy.
Maria Stefania SinicropiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, Arcavacata di Rende, 87036, Italy.
University of Calabria · ITUniversity of Basilicata · ITOspedale Policlinico San Martino · ITUniversity of Bari Aldo Moro · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) currently represents one of the most prevalent cancers among women worldwide and the leading cause of cancer death among women, also negatively affecting the quality of life (QoL) in patients. Over the past two decades, BC research has led to extraordinary advances in our understanding of the disease, resulting in more effective treatments. However, its occurrence is still increasing. Several new treatments are now under development worldwide, but they are not devoid of wellknown side effects, and a great number of patients develop endocrine resistance. Nevertheless, the design and synthesis of more suitable strategies and new drugs to treat breast cancers, overcome resistance and side effects, and obtain better therapeutic outcomes are needed. In this review, we summarize the therapies and the clinical studies currently ongoing in Italy for the treatment of BCs, mainly HER2+ MBC, HER2-low MBC, and TNBC, focusing on the most recent ones, also in consideration of diverse facets, including some aspects related to QoL. Finally, some studies related to the usefulness of physical activity in BC will be cited.

Indexed as

Breast NeoplasmsAntineoplastic AgentsErb-b2 Receptor Tyrosine KinasesFemaleHumansItalyQuality of LifeAntineoplastic AgentsErb-b2 Receptor Tyrosine KinasesBreast cancerHER2-low BCsHER2<sup>+</sup> MBCphysical activity.QoLTNBC

Identifiers

PMID38213176
OpenAlexW4390792929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.