ArticleRadiation oncology (London, England)2024
Prospects for daily online adaptive radiotherapy for cervical cancer: Auto-contouring evaluation and dosimetric outcomes.
Article in Radiation oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Prospective multi-institutional study of library-based adaptive radiotherapy for cervical cancer: Evaluation of plan-of-the-day selection and population analysis.Journal of applied clinical medical physics · 2025Trial
- Cone beam computed tomography guided online adaptive radiotherapy for cervical Cancer: Two-year single-Centre implementation and clinical experience.Technical innovations & patient support in radiation oncology · 2026Article
- Evaluation of online dose-guided adaptive fractionation for intact prostate radiotherapy.Journal of applied clinical medical physics · 2026Article
- The complementary roles of oversight, education, and collaboration in the responsible integration of artificial intelligence in radiation medicine: White paper of CADRA.Journal of applied clinical medical physics · 2026Review
- A bibliometric analysis of global research in cervical cancer radiotherapy (2015-2024): trends, hotspots, and future directions.Translational cancer research · 2026Article
- Artificial intelligence applications in adaptive radiotherapy-a narrative review.Translational cancer research · 2026Review
- A Comparative, Multiobserver Analysis of Nodal Contouring Methods in Pelvic Online Cone Beam-Based Adaptive Radiation Therapy.Advances in radiation oncology · 2026Article
- Commissioning and verification of a 3D Monte Carlo independent calculation software for O-ring linac systems.Journal of applied clinical medical physics · 2026Article
- Solution for the hot spots in adaptive radiotherapy planning for cervical cancer: a case report and review of literature.Frontiers in oncology · 2026Article
- Leveraging High-Fidelity Mode for Improved Online Adaptive Stereotactic Accelerated Partial Breast Treatment Efficiency.Advances in radiation oncology · 2025Article
- A Review on the Applications of Artificial Intelligence for Diagnosing and Treating Cervical Cancer.International journal of women's health · 2025Review
- Article
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Authors and funding
12 authors.
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Abstract
backgroundTraining senior radiation therapists as "adapters" to manage influencers and target editing is critical in daily online adaptive radiotherapy (oART) for cervical cancer. The purpose of this study was to evaluate the accuracy and dosimetric outcomes of automatic contouring and identify the key areas for modification.
methodsA total of 125 oART fractions from five postoperative cervical cancer patients and 140 oART fractions from five uterine cervical cancer patients treated with daily iCBCT-guided oART were enrolled in this prospective study. The same adaptive treatments were replanned using the Ethos automatic contours workflow without manual contouring edits. The clinical target volume (CTV) was subdivided into several separate regions, and the average surface distance dice (ASD), centroid deviation, dice similarity coefficient (DSC), and 95% Hausdorff distance (95% HD) were used to evaluate contouring for the above portions. Dosimetric results from automatic oART plans were compared to supervised oART plans to evaluate target volumes and organs at risk (OARs) dose changes.
resultsOverall, the paired CTV had high overlap rates, with an average DSC value greater than 0.75. The uterus had the largest consistency differences, with ASD, centroid deviation, and 95% HD being 2.67 ± 1.79 mm, 17.17 ± 12 mm, and 10.45 ± 5.68 mm, respectively. The consistency differences of the lower nodal CTV
conclusionsThe accuracy of automatic contouring from the Ethos adaptive platform is considered clinically acceptable for cervical cancer, and the uterus, upper vaginal cuff, and lower nodal CTV are the areas that need to be focused on in training.
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