ArticleNature nanotechnology2024
Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation.
Registry-linked trialOpen access · hybridAbstract read
In one paragraph
Article in Nature nanotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06368310 (First in Human), which is not on this map. Cited by 52 papers.
0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
30.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
First in Human (FIH) Clinical Investigation of Safety and Feasibility of a Novel Graphene Micro-electrocorticography Array for Brain Mapping in Neuro-oncology
Who cites it
52 citing papers in PubMed, 112 citations in OpenAlex.
- Multifunctional material platforms for neural interfaces: active orchestration of dynamic foreign body response across implantation lifetimes.Bioactive materials · 2026Review
- Processing graphene fibres by viscous flow.Nature materials · 2026Article
- A freestanding submicron electrocorticography electrode array.Nature communications · 2026Article
- Carbon based functional materials enable multifunctional flexible strain sensors for wearable and implantable applications.Discover nano · 2026Review
- Flexible laser-induced graphene biosensor enables real-time, in vivo profiling of wound healing cytokine dynamics.Journal of nanobiotechnology · 2026Article
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- PolyGraph - Flexible, Biocompatible & Electrically Optimized Graphene-Polymer Composites for Next-Generation Neural Interfaces.Advanced healthcare materials · 2026Article
- Mechanical properties of 3D graphene metamaterials with primitive three-period minimal surface.Journal of molecular modeling · 2026Article
- An artefact-resilient wide bandwidth bidirectional graphene neural interface.Nature communications · 2026Article
- Miniaturisation of a laser-scribed graphene electrode enables analyte detection at ultra-low concentrations.RSC advances · 2026Article
- In vitro bioactivity, cytotoxicity, and gene silencing of graphene oxide as a Bcl-2 siRNA carrier in osteosarcoma cells with in vivo inflammatory response.Scientific reports · 2026Article
- "Tone-Arm" Neuromodulation MEMS Microcoil for In Vivo Imaging.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Transparent Transfer-Free Ultrasmall Multilayer Graphene Microelectrodes Enable High Quality Recordings in Brain Slices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Two-dimensional semiconductor-based active array for high-fidelity spatiotemporal monitoring of neural activities.Nature materials · 2026Article
- Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A Closed-Loop-Capable Neural Interface Platform for Deep Brain Modulation via Integrated Non-Viral Gene Delivery, NIR Optogenetics, and Electrophysiological Recording.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Materials and System Design for Self-Decision Bioelectronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Biological performance evaluation of graphene nanoplatelets for intracranial direct current stimulation.Frontiers in neuroscience · 2026Article
- Advances in the treatment of blinding retinal diseases.International ophthalmology · 2025Review
- Multifunctional nanoplatforms for optic nerve regeneration integrating anti-inflammatory, epigenetic, and ionic mechanisms with emerging artificial intelligence technologies.Cell biology and toxicology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors at 6 institutions in 4 countries.
Damià Viana *Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Steven T Walston *Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0003-4567-8926
Eduard Masvidal-Codina *Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0002-9579-8603
Xavi IllaInstitut de Microelectrònica de Barcelona, IMB-CNM (CSIC), Campus UAB, Bellaterra, Spain.ORCID 0000-0002-3212-1128
Bruno Rodríguez-MeanaInstitute of Neurosciences, Department of Cell Biology, Physiology and Immunology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID 0000-0003-0052-7446
Jaume Del ValleInstitute of Neurosciences, Department of Cell Biology, Physiology and Immunology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Barcelona, Spain.
Andrew HaywardNanomedicine Lab, National Graphene Institute and Faculty of Biology, Medicine & Health, Manchester, UK.
Abbie DoddNanomedicine Lab, National Graphene Institute and Faculty of Biology, Medicine & Health, Manchester, UK.
Thomas LoretNanomedicine Lab, National Graphene Institute and Faculty of Biology, Medicine & Health, Manchester, UK.
Elisabet Prats-AlfonsoInstitut de Microelectrònica de Barcelona, IMB-CNM (CSIC), Campus UAB, Bellaterra, Spain.ORCID 0000-0002-7320-1896
Natàlia de la OlivaInstitute of Neurosciences, Department of Cell Biology, Physiology and Immunology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Barcelona, Spain.
Marie PalmaUniv. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, Grenoble, France.
Elena Del CorroCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0001-6452-9139
María Del Pilar BernicolaCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Elisa Rodríguez-LucasCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Thomas GenerCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0001-9209-9228
Jose Manuel de la CruzCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Miguel Torres-MirandaCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Fikret Taygun DuvanCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0002-3377-9351
Nicola RiaCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0002-0082-0952
Justin SperlingCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Sara Martí-SánchezCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Maria Chiara SpadaroCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Clément HébertCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.
Sinead SavageNanomedicine Lab, National Graphene Institute and Faculty of Biology, Medicine & Health, Manchester, UK.ORCID 0000-0002-1761-9390
Jordi ArbiolCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0002-0695-1726
Anton Guimerà-BrunetInstitut de Microelectrònica de Barcelona, IMB-CNM (CSIC), Campus UAB, Bellaterra, Spain.ORCID 0000-0003-1768-3293
M Victoria PuigCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain.ORCID 0000-0002-1490-4153
Blaise YvertUniv. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, Grenoble, France.ORCID 0000-0002-8850-7935
Xavier NavarroInstitute of Neurosciences, Department of Cell Biology, Physiology and Immunology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Barcelona, Spain.
Kostas KostarelosCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain. kostas.kostarelos@manchester.ac.uk.ORCID 0000-0002-2224-6672
Jose A GarridoCatalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Barcelona, Spain. joseantonio.garrido@icn2.cat.ORCID 0000-0001-5621-1067
Institut Català de Nanociència i Nanotecnologia · ESUniversitat Autònoma de Barcelona · ESInserm · FRInstitució Catalana de Recerca i Estudis Avançats · ESInstituto de Salud Carlos III · ESInstitut de Microelectrònica de Barcelona · ES
Funding
Wellcome Trust
Abstract
One of the critical factors determining the performance of neural interfaces is the electrode material used to establish electrical communication with the neural tissue, which needs to meet strict electrical, electrochemical, mechanical, biological and microfabrication compatibility requirements. This work presents a nanoporous graphene-based thin-film technology and its engineering to form flexible neural interfaces. The developed technology allows the fabrication of small microelectrodes (25 µm diameter) while achieving low impedance (∼25 kΩ) and high charge injection (3-5 mC cm
Indexed as
GraphiteNanoporesAnimalsElectric StimulationMicroelectrodesProstheses and ImplantsRatsGraphite
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
NCT06368310ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.