ArticlePediatric research2024
Delivery room intubation and neurodevelopment among extremely preterm infants.
Article in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Impact of attending neonatologist presence on neonatal intubation success and adverse events: a cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Optimal endotracheal tube insertion depth in infants with birth weights under 500 grams.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Impact of attending neonatologist presence on neonatal intubation success and adverse events: a cohort study.Research square · 2025Article
- Impact of LISA failure on 2-year neurodevelopmental outcomes in preterm infants: a retrospective cohort study.BMJ paediatrics open · 2025Article
- Neonatal Tracheal Intubation in the NICU: A Literature Review.Healthcare (Basel, Switzerland) · 2025Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of delivery room intubation (DRI) on neurodevelopment in extremely preterm infants remains unclear.
methodsWe retrospectively analyzed data for infants born at 24-27 gestational weeks between 2003 and 2018. The primary outcome was neurodevelopmental impairment (NDI), defined as cerebral palsy or hearing, visual, or cognitive impairment at age 3 years. Secondary outcomes were NDI components and death before and after discharge from the neonatal intensive care unit. We conducted robust Poisson regression analyses, adjusting for perinatal confounders.
resultsThe full cohort included 4397 infants with NDI data, of whom 3703 were intubated in the delivery room and 694 were not intubated in the delivery room. The mean gestational age and birth weight were 26.0 ± 1.1 weeks and 778 ± 184 g for infants with DRI and 26.6 ± 1.0 weeks and 873 ± 184 g for infants without DRI. Compared with infants without DRI, those with DRI had a higher risk for NDI (32.4% vs. 23.3%; adjusted risk ratio 1.18, 95% confidence interval: 1.01-1.37). There were no differences in secondary outcomes between infants with and without DRI.
conclusionsDRI was associated with an increased risk for NDI at age 3 years among extremely preterm infants. IMPACT: Few studies have examined the impact of delivery room intubation on neurodevelopment in infants born extremely preterm, and the results have been inconsistent. A total of 4397 infants born at 24-27 gestational weeks who had neurodevelopmental data at age 3 years were included in the present study. The present study found that delivery room intubation was associated with an increased risk for neurodevelopmental impairment at age 3 years among extremely preterm infants.
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