Evidence map›Paper›PMID 38212068›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trial.

Etienne Garin, Lambros Tselikas, Boris Guiu, Julia Chalaye, Yan Rolland, Thierry de Baere, Eric Assenat, Vania Tacher, Xavier Palard, Desirée Déandreis and 9 more

Abstract readRandomized Controlled TrialClinical Trial, Phase II
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Journal of gastrointestinal cancer · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Dosimetry-Driven Personalization of Radiopharmaceutical Therapies: Evidence and Opportunities.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  8. Review
  9. Article
  10. Predictive value of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Clinical Applications of Theranostics.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Etienne GarinCancer Institute Eugene Marquis, Rennes, France; e.garin@rennes.unicancer.fr.
Lambros TselikasGustave Roussy, University of Paris-Saclay, Villejuif, France.
Boris GuiuMontpellier University Hospital, Montpellier, France.
Julia ChalayeAP-HP, Hopitaux Universitaires Henri Mondor, Creteil, France.
Yan RollandCancer Institute Eugene Marquis, Rennes, France.
Thierry de BaereGustave Roussy, University of Paris-Saclay, Villejuif, France.
Eric AssenatMontpellier University Hospital, Montpellier, France.
Vania TacherAP-HP, Hopitaux Universitaires Henri Mondor, Creteil, France.
Xavier PalardCancer Institute Eugene Marquis, Rennes, France.
Desirée DéandreisGustave Roussy, University of Paris-Saclay, Villejuif, France.
Denis Mariano-GoulartMontpellier University Hospital, Montpellier, France.
Giuliana AmaddeoAP-HP, Hopitaux Universitaires Henri Mondor, Creteil, France.
Karim BoudjemaDepartment of Hepatobiliary and Digestive Surgery, CHU Rennes, Rennes, France.
Antoine HollebecqueGustave Roussy, University of Paris-Saclay, Villejuif, France.
Mohamad Azhar MeerunMontpellier University Hospital, Montpellier, France.
Helen RegnaultAP-HP, Hopitaux Universitaires Henri Mondor, Creteil, France.
Eric VibertCentre Hepato-Biliaire, Paul Brousse Hospital, AP-HP, Paris Saclay University, Villejuif, France; and.
Boris Campillo-GimenezCancer Institute Eugene Marquis, Rennes, France.
Julien EdelineCancer Institute Eugene Marquis, Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interim analysis of the DOSISPHERE-01 study demonstrated a strong improvement in response and overall survival (OS) on using

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsVenous ThrombosisHumansMicrospheresRadiometryYttrium RadioisotopesYttrium Radioisotopes90Y-loaded glass microspheresdownstagedhepatocellular carcinomapersonalized dosimetryportal vein thrombosis

Identifiers

PMID38212068
PMCPMC10858378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.