Evidence map›Paper›PMID 38212040›Full record

GuidelineAnnals of the rheumatic diseases2024

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update.

Tuva Moseng, Theodora P M Vliet Vlieland, Simone Battista, David Beckwée, Vladimira Boyadzhieva, Philip G Conaghan, Daniela Costa, Michael Doherty, Andrew G Finney, Tsvetoslav Georgiev and 15 more

2 registry-linked trialsOpen access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in Annals of the rheumatic diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 188 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 14 pooled it
109.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05670314 nacompletednot on this map

Molecular Signatures of Endocannabinoid Induced Pain Relief in Humans: Lifestyle Interventions, Systemic and Localised Changes

TypeinterventionalSponsorUniversity of NottinghamRan2022 to 2025Enrolled117ConditionsOsteoarthritis, KneeArmsInulin Fibre supplement, Maltodextrin (Placebo), Exercise
NCT07657481 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of the Effects of Two Different Home Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis: A Randomized Controlled Trial

TypeinterventionalSponsorPamukkale UniversityRan2026 to 2027Enrolled56ConditionsOsteo Arthritis of the KneeArmsQuadriceps Plus Hip Strengthening Exercises, Quadriceps Strengthening Exercises
3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 14 syntheses or guidelines pooled it, 233 citations in OpenAlex.

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  7. [2024 American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guideline: Management of Osteoarthritis of the Hip (summary) interpretation].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Guideline
  8. The Efficacy of Closed Versus Open Kinetic Chain Exercise in Knee Osteoarthritis-A Systematic Review and Meta-Analysis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Pooled it
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  12. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024
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128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 19 institutions in 11 countries.

Tuva MosengCenter for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway tuva.moseng@diakonsyk.no.ORCID http://orcid.org/0000-0003-0920-888X
Theodora P M Vliet VlielandDepartment of Orthopaedics, Rehabilitation and Physical Therapy, Leiden University Medical Center (LUMC), Leiden, Netherlands.ORCID http://orcid.org/0000-0001-6322-3859
Simone BattistaUniversity of Genoa Department of Neuroscience Ophthalmological Rehabilitation Genetics and Mother and Child Health, Genova, Italy.
David BeckwéeRehabilitation Research Department, Vrije Universiteit Brussel, Brussel, Belgium.
Vladimira BoyadzhievaUMHAT "St. Iv. Rilski" Clinic of Rheumatology, Medical University Sofia, Sofia, Bulgaria.
Philip G ConaghanLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomechanical Reserch Centre, Leeds, UK.ORCID http://orcid.org/0000-0002-3478-5665
Daniela CostaComprehensive Health Research Center (CHRC), Universidade Nova de Lisboa, Lisboa, Portugal.
Michael DohertyDepartment of Academic Rheumatology, University of Nottingham, Nottingham, UK.
Andrew G FinneyResearch Institute for Primary Care and Health Sciences, Keele University School of Medicine, Keele, UK.
Tsvetoslav GeorgievClinic of Rheumatology, University Hospital St. Marina, First Department of Internal Medicine, Medical University Varna, Varna, Bulgaria.
Milena GobboPositivamente Centro de Psicología, Madrid, Spain.
Norelee KennedySchool of Allied Health, Faculty of Education and Health Sciences and Health Research Institute, University of Limerick, Limerick, Ireland.
Ingvild KjekenCenter for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.
Féline P B KroonDepartment of Rheumatology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-8940-0582
L Stefan LohmanderDepartment of Clinical Sciences Lund, Orthopaedics, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0002-5424-9448
Hans LundCentre for Evidence-Based Practice, Western Norway University of Applied Sciences, Bergen, Norway.
Christian D MallenKeele University School of Medicine, Keele, UK.
Karel PavelkaInstitute of Rheumatology, Department of Rheumatology, Charles University First Faculty of Medicine, Praha, Czech Republic.
Irene A PitsillidouEULAR Patient Research Partner, Cyprus League Against Rheumatism, Nicosia, Cyprus.
Margaret P RaymanDepartment of Nutritional Sciences, University of Surrey Faculty of Health and Medical Sciences, Guildford, UK.
Anne Therese TveterCenter for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.
Johanna E VriezekolkResearch & Innovation, Sint Maartenskliniek, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0003-4783-8663
Dieter WiekEULAR Patient Research Partner, Deutsche Rheuma-Liga, Bonn, Germany.
Gustavo ZanoliOrthopaedic Ward, Casa di Cura Santa Maria Maddalena, Novara, Italy.
Nina ØsteråsCenter for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0001-8602-342X
Diakonhjemmet Hospital · NOKeele University · GBDeutsche Rheuma-Liga · DEInstitute of Rheumatology · CZLa Maddalena · ITLeiden University Medical Center · NLLund University · SEMedical University of Sofia · BGSint Maartenskliniek · NLUniversidade Nova de Lisboa · PTUniversity Hospital St. Marina · BGUniversity of Genoa · ITUniversity of Leeds · GBUniversity of Limerick · IEUniversity of Nottingham · GBUniversity of Surrey · GBVrije Universiteit Brussel · BEWestern Norway University of Applied Sciences · NOZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHip and knee osteoarthritis (OA) are increasingly common with a significant impact on individuals and society. Non-pharmacological treatments are considered essential to reduce pain and improve function and quality of life. EULAR recommendations for the non-pharmacological core management of hip and knee OA were published in 2013. Given the large number of subsequent studies, an update is needed.

methodsThe Standardised Operating Procedures for EULAR recommendations were followed. A multidisciplinary Task Force with 25 members representing 14 European countries was established. The Task Force agreed on an updated search strategy of 11 research questions. The systematic literature review encompassed dates from 1 January 2012 to 27 May 2022. Retrieved evidence was discussed, updated recommendations were formulated, and research and educational agendas were developed.

resultsThe revised recommendations include two overarching principles and eight evidence-based recommendations including (1) an individualised, multicomponent management plan; (2) information, education and self-management; (3) exercise with adequate tailoring of dosage and progression; (4) mode of exercise delivery; (5) maintenance of healthy weight and weight loss; (6) footwear, walking aids and assistive devices; (7) work-related advice and (8) behaviour change techniques to improve lifestyle. The mean level of agreement on the recommendations ranged between 9.2 and 9.8 (0-10 scale, 10=total agreement). The research agenda highlighted areas related to these interventions including adherence, uptake and impact on work.

conclusionsThe 2023 updated recommendations were formulated based on research evidence and expert opinion to guide the optimal management of hip and knee OA.

Indexed as

Exercise TherapyOsteoarthritis, HipOsteoarthritis, KneeEuropeEvidence-Based MedicineHumansPatient Education as TopicSelf-Help DevicesSelf-ManagementWeight LossOsteoarthritisOsteoarthritis, KneePhysical Therapy ModalitiesRehabilitationTherapeutics

Identifiers

PMID38212040
PMCPMC11103326
OpenAlexW4390753804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.