Evidence map›Paper›PMID 38211725›Full record

ArticleContemporary clinical trials2024

Design of a hybrid implementation effectiveness cluster randomized controlled trial of delivering written exposure therapy for PTSD in underserved primary care settings.

Lisa S Meredith, Eunice C Wong, Brian P Marx, Bing Han, Ariella R Korn, Jonathan N Tobin, Andrea Cassells, Stephanie Williamson, Meghan Franco, Cleo Clarize Overa and 3 more

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05330442 (Delivering Written Exposure Therapy for PTSD in Underserved Primary Care Settings), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05330442 naactive not recruitingnot on this map

Delivering Written Exposure Therapy for PTSD in Underserved Primary Care Settings

TypeinterventionalSponsorRANDRan2022 to 2027Enrolled720ConditionsPTSDArmsWritten Exposure Therapy (WET)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Lisa S MeredithRAND Corporation, Santa Monica, CA, United States of America; VA HSR&D Center for Healthcare Innovation, Implementation & Policy, Sepulveda, CA, United States of America. Electronic address: lisa_meredith@rand.org.
Eunice C WongRAND Corporation, Santa Monica, CA, United States of America.
Brian P MarxNational Center for PTSD, Behavioral Science Division at VA Boston Healthcare, Boston, MA, United States of America; Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States of America.
Bing HanKaiser Permanente Southern California, Department of Research & Evaluation, Pasadena, CA, United States of America.
Ariella R KornRAND Corporation, Boston, MA 02116, United States of America.
Jonathan N TobinClinical Directors Network (CDN), New York, NY, United States of America; The Rockefeller University Center for Clinical and Translational Science, New York, NY, United States of America.
Andrea CassellsClinical Directors Network (CDN), New York, NY, United States of America.
Stephanie WilliamsonRAND Corporation, Santa Monica, CA, United States of America.
Meghan FrancoPardee RAND Graduate School, Santa Monica, CA, United States of America.
Cleo Clarize OveraClinical Directors Network (CDN), New York, NY, United States of America.
Tameir HolderClinical Directors Network (CDN), New York, NY, United States of America.
T J LinClinical Directors Network (CDN), New York, NY, United States of America.
Denise M SloanNational Center for PTSD, Behavioral Science Division at VA Boston Healthcare, Boston, MA, United States of America; Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States of America.
Clinical Directors Network · USRAND Corporation · USBoston University · USCenter for the Study of Healthcare Provider Behavior · USFrederick S. Pardee RAND Graduate School · USKaiser Permanente · USNational Center for PTSD · USRockefeller University · US

Funding

Delivering Written Exposure Therapy for PTSD in Underserved Primary Care SettingsR01MH123585 · NIMH · RAND CORPORATION · PI MEREDITH, LISA SEIDEL, SLOAN, DENISE M. · 2021 to 2025
$5.9M
NIMH NIH HHS R01 MH123585
6 · The paper itself

Abstract

introductionPosttraumatic stress disorder (PTSD) results in substantial costs to society. Prevalence of PTSD among adults is high, especially among those presenting to primary care settings. Evidence-based psychotherapies (EBPs) for PTSD are available but dissemination and implementation within primary care settings is challenging. Building Experience for Treating Trauma and Enhancing Resilience (BETTER) examines the effectiveness of integrating Written Exposure Therapy (WET) within primary care collaborative care management (CoCM). WET is a brief exposure-based treatment that has the potential to address many challenges of delivering PTSD EBPs within primary care settings.

methodsThe study is a hybrid implementation effectiveness cluster-randomized controlled trial in which 12 Federally Qualified Health Centers (FQHCs) will be randomized to either CoCM plus WET (CoCM+WET) or CoCM only with 60 patients within each FQHC. The primary aim is to evaluate the effectiveness of CoCM+WET to improve PTSD and depression symptom severity. Secondary treatment outcomes are mental and physical health functioning. The second study aim is to examine implementation of WET within FQHCs using FQHC process data and staff interviews pre- and post-intervention. Exploratory aims are to examine potential moderators and mediators of the intervention. Assessments occur at baseline, and 3- and 12-month follow-up.

conclusionThe study has the potential to impact practice and improve clinical and public health outcomes. By establishing the effectiveness and feasibility of delivering a brief trauma-focused EBP embedded within CoCM in primary care, the study aims to improve PTSD outcomes for underserved patients.

trial registration(Clinicaltrials.govNCT05330442).

Indexed as

Implosive TherapyStress Disorders, Post-TraumaticAdultCrisis InterventionHumansPrimary Health CareRandomized Controlled Trials as TopicTreatment OutcomeBrief psychotherapyCollaborative careEvidence-based psychotherapy (EBP)Federally Qualified Health Centers (FQHCs)PTSD

Identifiers

PMID38211725
PMCPMC11146292
OpenAlexW4390781752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.