Evidence map›Paper›PMID 38206561›Full record

ArticleVeterinary research communications2024

First serological diagnosis of Mycobacterium avium subsp. paratuberculosis infection in sheep in the state of Pernambuco, Brazil.

Amanda de Noronha Xavier, Luenda Menezes Novaes de Sá, Maria de Nazaré Santos Ferreira, Pollyanne Raysa Fernandes de Oliveira, Rodolfo de Moraes Peixoto, Rinaldo Aparecido Mota, José Wilton Pinheiro Junior

Abstract read
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In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prevalence and Genotyping ofVeterinary sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amanda de Noronha XavierDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil. amandadenoronha@gmail.com.
Luenda Menezes Novaes de SáFederal Institute of the Pernambuco Sertão, Floresta Campus, Rua Projetada, s/n - Caetano II, Floresta, PE, 56400-000, Brazil.
Maria de Nazaré Santos FerreiraDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil.
Pollyanne Raysa Fernandes de OliveiraDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil.
Rodolfo de Moraes PeixotoFederal Institute of the Pernambuco Sertão, Campus Petrolina - Rural Zone, PE 647, Km 22, PISNC N - 4, Zona Rural, Petrolina, PE, 56302-970, Brazil.
Rinaldo Aparecido MotaDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil.
José Wilton Pinheiro JuniorDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to diagnose Mycobacterium avium subsp. paratuberculosis (MAP) infections in sheep in the state of Pernambuco, Brazil. A total of 276 blood samples were analyzed using the enzyme-linked immunosorbent assay IDEXX Paratuberculosis Screening kit, and 261 fecal samples were submitted for bacterial culture and polymerase chain reaction tests. An animal-level sero-frequency of 0.72% (n = 2/276) and a farm-level sero-frequency of 20% (n = 2/10) were found. All fecal sample cultures were negative, and molecular analyses were also negative. To the best of our knowledge, this is the first study of MAP infection in sheep in the state of Pernambuco and one of the pioneers in the country. It is an asymptomatic disease that is difficult to diagnose in this species because the susceptibility of sheep to the organism is lower than that of other ruminant species. However, the sero-frequency found reveals that there is MAP exposure in sheep flocks in the region. In addition, serological monitoring can contribute to the observation of the organism's behavior in herds. Our results support the potential risk of MAP infection in sheep in the state of Pernambuco, Brazil.

Indexed as

Cattle DiseasesMycobacterium avium subsp. paratuberculosisParatuberculosisSheep DiseasesAnimalsBrazilCattleEnzyme-Linked Immunosorbent AssayFecesPolymerase Chain ReactionSheepAntibodyJohne’s diseaseOvineParatuberculosisPrevalence

Identifiers

PMID38206561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.