Evidence map›Paper›PMID 38206517›Full record

SynthesisClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2024

Expert-based collaborative analysis of the situation and prospects of biomarker test implementation in oncology in Spain.

Jorge Mestre-Ferrándiz, Blanca Franch Camino, Álvaro Hidalgo, Alicia Del Llano Núñez-Cortés, Juan Ernesto Del Llano Señarís, Blanca Lumbreras, David Beas Pedraza, Roberto Nuño-Solinís, Luis Paz-Ares, Santiago Ramón Y Cajal and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jorge Mestre-FerrándizUniversidad Carlos III, Madrid, Spain.
Blanca Franch CaminoFundación Gaspar Casal, Madrid, Spain.
Álvaro HidalgoFundación Weber, Madrid, Spain.
Alicia Del Llano Núñez-CortésFundación Gaspar Casal, Madrid, Spain.
Juan Ernesto Del Llano SeñarísFundación Gaspar Casal, Madrid, Spain. juan.delllano@fgcasal.org.ORCID http://orcid.org/0000-0002-2191-8991
Blanca LumbrerasUniversidad Miguel Hernández (UMH), Elche, Spain.
David Beas PedrazaJanssen España, Madrid, Spain.
Roberto Nuño-SolinísAES, Madrid, Spain.
Luis Paz-AresHospital Universitario 12 Octubre, Madrid, Spain.
Santiago Ramón Y CajalHospital de Vall d'Hebron, Barcelona, Spain.
Miguel Javier RodríguezHospital Universitario Central de Asturias, Oviedo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBiomarkers as screening for precision medicine is a fundamental step. The purpose of this article is twofold. First, to highlight the existing barriers in the implementation of Precision Medicine in Spain, with a special emphasis on barriers in access to the determination of biomarkers. Second, to provide a Roadmap that can help implement Precision Medicine equitably at the national level and optimize the use of biomarkers.

methodsA systematic review of literature (SRL) and a focus group (FG) with multidisciplinary experts has been carried out in 2023. Participants were contacted individually, and discourse analysis was processed anonymously.

resultsWe carried out a quantitative (SRL) and a qualitative approach (FG). The discourse analysis and roadmap were sent individually to each expert for approval.

conclusionsThe potential of Precision Medicine has not been fulfilled in Spain. While several regional initiatives are in place, a national plan or strategy around Precision Medicine and use of biomarkers is lacking. In a general context of rapid progress at a global and European level, including the 2021 Europe's Beating Cancer Plan, it is time to define and implement a National Plan to make the promise come true. While some comparable countries within Europe - such as the UK or France - are mature enough to adopt such strategies, in Spain there is still a long way to go. We consider that the different strands of work outlined in the Roadmap can be used as basis for such purpose.

Indexed as

Biomarkers, TumorMedical OncologyNeoplasmsPrecision MedicineFocus GroupsHumansSpainBiomarkers, TumorBiomarkersOncologyPolicy RoadmapPrecision MedicineSpain

Identifiers

PMID38206517
PMCPMC10981580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.