Evidence map›Paper›PMID 38206473›Full record

ArticleJournal of materials science. Materials in medicine2024

Oxali-palladium nanoparticle synthesis, characterization, protein binding, and apoptosis induction in colorectal cancer cells.

Nasim Golestannezhad, Adeleh Divsalar, Farideh Badalkhani-Khamseh, Milad Rasouli, Arefeh Seyedarabi, Behafarid Ghalandari, Xianting Ding, Fatemeh Goli, Sander Bekeschus, Ali Akbar Moosavi Movahedi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Nasim GolestannezhadDepartment of Cell & Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, 49 Dr. Mofatteh Ave, 31979-37551, Tehran, Iran.
Adeleh DivsalarDepartment of Cell & Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, 49 Dr. Mofatteh Ave, 31979-37551, Tehran, Iran. divsalar@khu.ac.ir.ORCID http://orcid.org/0000-0002-8809-5280
Farideh Badalkhani-KhamsehDepartment of Physical Chemistry, Faculty of Sciences, Tarbiat Modares University, Jalale-Al-Ahmad Ave, P.O. Box 14117-13116, Tehran, Iran.
Milad RasouliDepartment of Physics, Kharazmi University, 49 Dr. Mofatteh Ave, Tehran, 15614, Iran.
Arefeh SeyedarabiInstitute of Biochemistry and Biophysics (IBB), Tehran University, Tehran, 1417614418, Iran.
Behafarid GhalandariState Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Xianting DingState Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Fatemeh GoliDepartment of Cell & Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, 49 Dr. Mofatteh Ave, 31979-37551, Tehran, Iran.
Sander BekeschusZIK Plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Felix-Hausdorff-Str. 2, 17489, Greifswald, Germany.
Ali Akbar Moosavi MovahediInstitute of Biochemistry and Biophysics (IBB), Tehran University, Tehran, 1417614418, Iran.
Mahboube Eslami MoghadamChemistry & Chemical Engineering Research Center of Iran, Pajohesh Blvd,17th Km of Tehran-Karaj Highway, 1497716320, Tehran, Iran.
Kharazmi University · IRShanghai Jiao Tong University · CNUniversity of Tehran · IRChemistry and Chemical Engineering Research Center of Iran · IRLeibniz Institute for Plasma Science and Technology · DETarbiat Modares University · IR

Funding

Iran National Science Foundation 99004364Kharazmi University 1400
6 · The paper itself

Abstract

This paper focuses on the synthesis of nano-oxali-palladium coated with turmeric extract (PdNPs) using a green chemistry technique based on the reduction in the Pd (II) complex by phytochemicals inherent in turmeric extract. PdNPs were examined and characterized using Field Emission Scanning Electron Microscopy (FESEM), Dynamic Light Scattering (DLS), Fourier Transform Infrared (FTIR), and Atomic Force Microscopy (AFM). Using different spectroscopic and molecular dynamics simulations, a protein-binding analysis of the produced nanoparticle was conducted by observing its interaction with human serum albumin (HSA). Lastly, the cytotoxic effects and apoptotic processes of PdNPs were studied against the HCT116 human colorectal cell line using the MTT assay and flow cytometry tests. According to the findings, PdNPs with spherical and homogenous morphology and a size smaller than 100 nm were generated. In addition, they can induce apoptosis in colorectal cancer cells in a dose-dependent manner with a lower Cc

Indexed as

Colorectal NeoplasmsNanoparticlesOxalidaceaeApoptosisHumansPalladiumProtein BindingPalladium

Identifiers

PMID38206473
PMCPMC10784377
OpenAlexW4390746866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.