Evidence map›Paper›PMID 38206164›Full record

Observational studyRadiology. Cardiothoracic imaging2024

Echocardiography versus Cardiac MRI for Measurement of Left Ventricular Ejection Fraction in Individuals with Cancer and Suspected Cardiotoxicity.

Muhummad Sohaib Nazir, Joseph Okafor, Theodore Murphy, Maria Sol Andres, Sivatharshini Ramalingham, Stuart D Rosen, Amedeo Chiribiri, Sven Plein, Sanjay Prasad, Raad Mohiaddin and 4 more

Erratum issuedOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. World journal of nuclear medicine · 2026
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  11. Cardio-Oncology and Multi-Imaging Modalities.Journal of clinical medicine · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Muhummad Sohaib NazirFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0003-2749-1033
Joseph OkaforFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0002-1021-6134
Theodore MurphyFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).
Maria Sol AndresFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0002-9554-2026
Sivatharshini RamalinghamFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0009-0009-2582-9548
Stuart D RosenFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0001-8034-0037
Amedeo ChiribiriFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0003-3394-4289
Sven PleinFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0002-0997-4384
Sanjay PrasadFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).
Raad MohiaddinFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0002-1768-7457
Dudley J PennellFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0001-5523-1314
A John BaksiFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).ORCID 0000-0001-5492-1743
Rajdeep KhattarFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).
Alexander R LyonFrom the Cardio-Oncology Service (M.S.N., T.M., M.S.A., S.R., S.D.R., A.R.L.), Department of Echocardiography (J.O., R.K.), and Cardiovascular Magnetic Resonance Unit (S. Prasad, R.M., D.J.P., A.J.B.), Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London SE1 7EU, United Kingdom (M.S.N., A.C., S. Plein); and National Heart & Lung Institute, Imperial College London, London, United Kingdom (S.D.R., S. Prasad, R.M., D.J.P., A.J.B., A.R.L.).
Royal Society · GB

Funding

British Heart Foundation CH/16/2/32089British Heart Foundation RG/19/1/34160
6 · The paper itself

Abstract

Purpose To compare left ventricular ejection fraction (LVEF) measured with echocardiography and cardiac MRI in individuals with cancer and suspected cardiotoxicity and assess the potential effect on downstream clinical decision-making. Materials and Methods In this prospective, single-center observational cohort study, participants underwent same-day two-dimensional (2D) echocardiography and cardiac MRI between 2011 and 2021. Participants with suboptimal image quality were excluded. A subset of 74 participants also underwent three-dimensional (3D) echocardiography. The agreement of LVEF derived from each modality was assessed using Bland-Altman analysis and at relevant thresholds for cardiotoxicity. Results A total of 745 participants (mean age, 60 years ± 5 [SD]; 460 [61.7%] female participants) underwent same-day echocardiography and cardiac MRI. According to Bland-Altman analysis, the mean bias was -3.7% ± 7.6 (95% limits of agreement [LOA]: -18.5% to 11.1%) for 2D echocardiography versus cardiac MRI. In 74 participants who underwent cardiac MRI, 3D echocardiography, and 2D echocardiography, the mean LVEFs were 60.0% ± 10.4, 58.4% ± 9.4, and 57.2% ± 8.9, respectively (

Indexed as

NeoplasmsVentricular Function, LeftCardiotoxicityEchocardiographyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesStroke VolumeCardiacEchocardiographyMR Functional Imaging

Identifiers

PMID38206164
PMCPMC10912891
OpenAlexW4390764463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.