Evidence map›Paper›PMID 38205943›Full record

ArticleCancer medicine2024

A prospective study of the relationship between illness perception, depression, anxiety, and quality of life in hematopoietic stem cell transplant patients.

Steven C Ames, Lori Lange, Gretchen E Ames, Michael G Heckman, Launia J White, Vivek Roy, James M Foran

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Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Steven C AmesDivision of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, Florida, USA.ORCID 0009-0004-3596-5627
Lori LangeDepartment of Psychology, University of North Florida, Jacksonville, Florida, USA.
Gretchen E AmesDepartment of Psychiatry and Psychology, Mayo Clinic Florida, Jacksonville, Florida, USA.
Michael G HeckmanDivision of Clinical Trials and Biostatistics, Mayo Clinic Florida, Jacksonville, Florida, USA.
Launia J WhiteDivision of Clinical Trials and Biostatistics, Mayo Clinic Florida, Jacksonville, Florida, USA.
Vivek RoyDivision of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, Florida, USA.
James M ForanDivision of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, Florida, USA.ORCID 0000-0003-1673-1708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of study was to investigate whether depression and anxiety symptoms and illness perception prior to hematopoietic stem cell transplantation (HSCT) predict health related quality of life (HRQOL) at Day 100 and 1 year following HSCT.

methodsA total of 205 patients who underwent HSCT (N = 127 autologous transplants, N = 78 allogeneic transplants) were included in this prospective study. Baseline assessment was assessed prior to transplantation and post HSCT data were collected at Day 100 and 1 year. At baseline we assessed depressive symptoms (Patient Health Questionnaire-9), anxiety symptoms (Generalized Anxiety Disorder-7), illness perception (Brief Illness Perception Questionnaire), and HRQOL (Functional Assessment of Cancer Therapy-BMT).

resultsPatients who expressed a greater level of concern about the severity, course, and ability to exert control over one's illness (i.e., illness perception) and who reported a greater level of depression and anxiety symptoms prior to HSCT reported lower HRQOL at both Day 100 and 1 year posttransplant, with a similar degree of association observed at the two follow-up time points.

conclusionsOur findings suggest that pretransplant perceptions about their illness and negative mood are significant predictors of HRQOL following HSCT. Illness perception, depression, and anxiety are potentially modifiable risk factors for less than optimal outcome after HCSCT and intervention strategies should be explored.

Indexed as

Hematopoietic Stem Cell TransplantationQuality of LifeAnxietyAnxiety DisordersDepressionHumansPerceptionProspective Studiesbehavioral sciencecancer stem cellsQOLquality of life

Identifiers

PMID38205943
PMCPMC10905249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.