Evidence map›Paper›PMID 38205893›Full record

ArticleJournal of veterinary internal medicine

Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia.

Petra Černá, Cristobal Lopez-Jimenez, Kenjiro Fukushima, Ko Nakashima, Taisuke Nakagawa, Fiona Adam, Anna Groth, Andrew Denning, Nicolas Israeliantz, Danièlle A Gunn-Moore

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Petra ČernáDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0002-4300-8534
Cristobal Lopez-JimenezNorth Downs Specialist Referrals, Bletchingley, UK.
Kenjiro FukushimaVeterinary Specialists & Emergency Center, Kawaguchi-shi, Saitama, Japan.
Ko NakashimaSmall Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-4823-4821
Taisuke NakagawaVeterinary Medical Centre, The University of Tokyo, Tokyo, Japan.
Fiona AdamNorth Downs Specialist Referrals, Bletchingley, UK.
Anna GrothNorth Downs Specialist Referrals, Bletchingley, UK.
Andrew DenningNorth Downs Specialist Referrals, Bletchingley, UK.
Nicolas IsraeliantzThe Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.ORCID https://orcid.org/0000-0002-8472-094X
Danièlle A Gunn-MooreThe Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.
North Downs Hospital · GBRoslin Institute · GBJapan Small Animal Medical Center · JPSaitama Prefectural Industrial Technology Center · JPTokyo Medical University · JPUniversity of Veterinary Sciences Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal eosinophilic sclerosing fibroplasia (GESF) in cats presents as mass(es) associated with the gastrointestinal tract, mesentery, and abdominal lymph nodes. HYPOTHESIS/

objectivesTo report the clinicopathological findings, treatment, and outcome of cats with GESF. ANIMALS: Sixty client-owned cats diagnosed with GESF.

methodsRetrospective review of medical records of cats with histopathologically confirmed GESF.

resultsThe median age was 5.4 years (interquartile range [IQR], 3.3-8.9.); 30% were Domestic Shorthairs and 12% were Domestic Longhair cats, with the most prevalent pedigree breeds being Ragdolls (25%), Exotic Shorthair (10%) and Persian (8%) cats. The median duration of clinical signs was 90 days (IQR, 17.5-247.0); the most common clinical signs were weight loss (60%), hyporexia/anorexia (55%), chronic vomiting (37%), lethargy (35%) and chronic diarrhea (27%). Masses were located in the small intestine (32%), stomach (27%), ileocolic junction (15%), colon (10%), lymph node (8%) and mesentery (8%) and 15% of cats had >1 mass. Eosinophilia was present in 50% and hypoalbuminemia in 28% of cats. The mass was removed surgically in 37% of cases. Most cats (98%) were treated with corticosteroids. Survival was not statistically different between cats treated with surgical resection and cats treated with medical therapy alone, 88% of the cats were still alive at the time of writing. CONCLUSIONS AND CLINICAL IMPORTANCE: GESF is an important differential diagnosis for abdominal masses in cats, and has a much better prognosis than previously reported.

Indexed as

Cat DiseasesEnteritisEosinophiliaGastritisAnimalsCatsHumansRetrospective StudiesTreatment Outcomeeosinophiliagastrointestinal massmesenteric massragdoll

Identifiers

PMID38205893
PMCPMC10937490
OpenAlexW4390741122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.