Evidence map›Paper›PMID 38205657›Full record

ArticleThe International journal of eating disorders2024

Clinical characteristics of hospitalized male adolescents and young adults with atypical anorexia nervosa.

Jason M Nagata, Ruben Vargas, Austin E Sanders, Elena Stuart, Amanda E Downey, Anita V Chaphekar, Anthony Nguyen, Kyle T Ganson, Sara M Buckelew, Andrea K Garber

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Thorny Issue of Atypical Anorexia Nervosa: Clinicians' Perspectives on How It Should Be Defined.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Jason M NagataDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0002-6541-0604
Ruben VargasDepartment of Pediatrics, University of California, San Francisco, California, USA.
Austin E SandersDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0001-7308-2797
Elena StuartDepartment of Pediatrics, University of California, San Francisco, California, USA.
Amanda E DowneyDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0002-5206-7798
Anita V ChaphekarDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0002-8326-9077
Anthony NguyenDepartment of Pediatrics, University of California, San Francisco, California, USA.
Kyle T GansonFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-3889-3716
Sara M BuckelewDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0001-8252-0293
Andrea K GarberDepartment of Pediatrics, University of California, San Francisco, California, USA.ORCID 0000-0002-7563-0651
University of California, San Francisco · USUniversity of Toronto · CA

Funding

Multi-center Randomized Controlled Trial of Refeeding in Anorexia NervosaR01HD082166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARBER, ANDREA K · 2015 to 2025
$5.7M
Investigating relationships between problematic social media use and binge-eating disorder to inform precision guidance for adolescentsR01MH135492 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2023 to 2024
$1.0M
Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular diseaseK08HL159350 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2021 to 2025
$869k
NHLBI NIH HHS K08 HL159350NHLBI NIH HHS K08HL159350NICHD NIH HHS R01 HD082166NIMH NIH HHS R01 MH135492NIMH NIH HHS R01MH135492
6 · The paper itself

Abstract

objectiveTo describe the clinical characteristics of male adolescents and young adults hospitalized for medical complications of atypical anorexia nervosa (atypical AN) and to compare their clinical characteristics with females with atypical AN and males with anorexia nervosa (AN).

methodA retrospective review of electronic medical records for patients with atypical AN and AN aged 9-25 admitted to the UCSF Eating Disorders Program from May 2012 to August 2020 was conducted.

resultsAmong 21 males with atypical AN (mean age 15.1 ± 2.7, mean %mBMI 102.0 ± 11.8), medical complications evidenced by admission laboratory values included anemia (52.9%), vitamin D insufficiency/deficiency (52.6%), and zinc deficiency (31.6%). Compared with females with atypical AN (n = 69), males with atypical AN had longer length of stay (11.4 vs 8.4 days, p = .004), higher prescribed kcal at discharge (4114 vs 3045 kcal, p < .001), lower heart rate nadir (40.0 vs 45.8, p = .038), higher aspartate transaminase (AST, 37.9 vs 26.2 U/L, p = .032), higher alanine transaminase (ALT, 30.6 vs 18.3 U/L, p = .005), and higher rates of anemia (52.9% vs 19.4%, p = .005), with no differences in vitamin D, zinc, and vital signs. Compared with males with AN (n = 40), males with atypical AN had no significant differences in vital signs or laboratory assessments during the hospitalization. DISCUSSION: Atypical AN in males leads to significant medical comorbidity, and males with atypical AN require longer hospital stays compared to females with atypical AN. Rates of abnormal vital signs and abnormal serum laboratory values during hospital admissions do not differ in males with atypical AN compared to AN. PUBLIC SIGNIFICANCE: Adolescent and young adult males with atypical anorexia nervosa experience significant medical complications. Males with atypical anorexia nervosa had longer hospitalizations and higher prescribed nutrition at discharge than females. Medical complications of atypical anorexia nervosa in male adolescents and young adults were generally equal to those of male adolescents and young adults with anorexia nervosa. Clinicians should be aware of unique medical complications of males with atypical anorexia nervosa.

Indexed as

AnemiaAnorexia NervosaAdolescentBody Mass IndexChildFemaleHospitalizationHumansMaleYoung AdultZincZincanorexia nervosaatypical anorexia nervosafeeding and eating disordersfemalemalerefeeding

Identifiers

PMID38205657
PMCPMC11018472
OpenAlexW4390743619

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.