Evidence map›Paper›PMID 38205489›Full record

ArticleCureus2023

Genetic Disorders Underlying Polyhydramnios and Congenital Hypotonia: Three Case Reports and a Review of the Literature.

Niki Dermitzaki, Themistoklis Loukopoulos, Athanasios Zikopoulos, Anastasia Vatopoulou, Sofoklis Stavros, Chara Skentou

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Niki DermitzakiNeonatal Intensive Care Unit, University Hospital of Ioannina, Ioannina, GRC.
Themistoklis LoukopoulosMedicine, University of Ioannina, Ioannina, GRC.
Athanasios ZikopoulosObstetrics and Gynecology, Royal Cornwall Hospital, Cornwall, GBR.
Anastasia VatopoulouObstetrics and Gynecology, University Hospital of Ioannina, Ioannina, GRC.
Sofoklis StavrosObstetrics and Gynecology, University Hospital Attikon, National and Kapodistrian University of Athens, Athens, GRC.
Chara SkentouObstetrics and Gynecology, University of Ioannina, Ioannina, GRC.
Royal Cornwall Hospital Trust · GBUniversity General Hospital Attikon · GRUniversity Hospital of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An abnormal rise in the amount of amniotic fluid is a frequent prenatal observation called polyhydramnios, which can indicate a number of underlying problems. Even while it frequently goes undiagnosed during pregnancy, it may be linked to dangerous fetal illnesses. In three cases of newborns with congenital hypotonia, polyhydramnios was the sole prenatal symptom reported in this study. This fact highlights the significance of understanding the possible connection between genetic abnormalities or neurological problems and polyhydramnios, underscoring the responsibility obstetricians have in educating expectant mothers who are at potential risk for these uncommon but serious illnesses. Whole-genome sequencing (WES), an advanced kind of prenatal testing, is essential for determining genetic reasons and assisting families in making decisions. Working together with specialists in fetal medicine is crucial in guaranteeing the best possible treatment and results for the mother and child.

Indexed as

fetal medicinegenetic disordersneaonatal neurological disordersobstetric counselingpolyhydramniosprenatal diagnosis

Identifiers

PMID38205489
PMCPMC10779346
OpenAlexW4389550580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.