Evidence map›Paper›PMID 38205383›Full record

ArticleArab journal of urology2024

Prevalence and risk factors of erectile dysfunction in cirrhotic patients: An observational study.

Mohamed Fakhry, Hamdy Mahfouz, Khalid Abdelazeem, Mohamed AbdelSabour, Nour Shaheen, Ahmed Fathy, Amro M Hassan, Hazem Dief, Mohamed El-Nady, Mustafa A Haridy and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Mohamed FakhryHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Hamdy MahfouzHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Khalid AbdelazeemHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Mohamed AbdelSabourDermatology, Andrology and Venereal Diseases Department, Faculty of Medicine Al-Azhar University, Assiut, Egypt.
Nour ShaheenFaculty of Medicine, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0001-8663-4044
Ahmed FathyHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Amro M HassanHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Hazem DiefUrology Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Mohamed El-NadyInternal Medicine, Kasr El-Einy School of Medicine, Cairo University, Cairo, Egypt.
Mustafa A HaridyHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Omran MohamedHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Safwat SalamaHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Emad AbdelrazzakHepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Walid SaberInternal Medicine, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Tarek MohamedRadiodiagnosis Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Maha MohamedDepartment of Tropical Medicine and Gastroenterology, Sohag University, Assiut, Egypt.
Wael EsmatClinical Pathology Department, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Eman FathyDepartment of Dermatology, Venerology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Muhamed AbdelrahimDepartment of Tropical Medicine and Gastroenterology, Assiut University, Assiut, Egypt.
Rasha MareeDepartment of Tropical Medicine and Gastroenterology, Assiut University, Assiut, Egypt.
Al-Azhar University · EGAssiut University · EGAlexandria University · EGCairo University · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Erectile dysfunction (ED) is a prevalent complication observed in male patients with liver cirrhosis; however, there is limited understanding of the etiological determinants responsible for its occurrence. The objective of this investigation is to explore potential contributory factors that underlie the development of ED in male patients with liver cirrhosis. Method: A cross-sectional study was conducted on 200 male patients with liver cirrhosis, who were divided into three groups according to the Child score. ED was studied using the International Index of Erectile Function (IIEF-5) Questionnaire and penile Doppler. Results: The prevalence of ED among the cirrhotic patients was 80%, and it was more frequent in patients with advanced liver disease (Child C). Penile venous leakage was observed in 20% of cirrhotic patients, which increased to 28.6% in those with advanced liver cirrhosis. Multivariate logistic regression analysis showed that age, low albumin levels, elevated INR, high hemoglobin levels, and Child C were predictors of ED in cirrhotic patients. Conclusion: Several clinical variables have been identified as potential contributors to the development of erectile dysfunction (ED) in patients with cirrhosis. These variables include advanced age, decreased levels of albumin, elevated INR, increased hemoglobin levels, and Child C classification. Early identification and treatment of these factors could potentially improve the quality of life for cirrhotic patients with ED. Notably, patients with ED in this population were observed to have elevated levels of INR, serum bilirubin, and hemoglobin, as well as reduced levels of serum albumin.

Indexed as

Erectile dysfunctionHCVliver cirrhosis

Identifiers

PMID38205383
PMCPMC10776039
OpenAlexW4385245708

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.