Evidence map›Paper›PMID 38205132›Full record

ArticleAJOG global reports2024

Prenatal aneuploidy screening in a low-risk Hispanic population: price elasticity and cost-effectiveness.

Caitlin M Clifford, Neil Askew, Diane Smith, Jesus Iniguez, Andrew Smith, Michael D House, Ashley A Leech

Open access · goldAbstract read
In one paragraph

Article in AJOG global reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Caitlin M CliffordDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA (Dr Clifford).
Neil AskewDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, TN (Mr Askew and Dr Leech).
Diane SmithGreater Lawrence Family Health Center, Lawrence, MA (Drs Smith and Iniquez).
Jesus IniguezGreater Lawrence Family Health Center, Lawrence, MA (Drs Smith and Iniquez).
Andrew SmithVanderbilt Center for Child Health Policy, Vanderbilt University Medical Center, Nashville, TN (Drs Smith and Leech).
Michael D HouseDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI (Drs Clifford and House).
Ashley A LeechDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, TN (Mr Askew and Dr Leech).
Greater Lawrence Family Health Center · USVanderbilt University · USTufts Medical Center · USVanderbilt University Medical Center · US

Funding

Advancing Treatment Outcomes for Pregnant Women with Opioid Use DisorderK01DA050740 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LEECH, ASHLEY A · 2020 to 2024
$860k
NIDA NIH HHS K01 DA050740
6 · The paper itself

Abstract

backgroundIn October 2015, the Massachusetts Medicaid program temporarily stopped reimbursement for procedures in which the International Classification of Diseases, Tenth Edition, code for serum aneuploidy screening used by certain communities was stipulated. This change led to a substantial number of patients who went without aneuploidy screening for approximately 3 years.

objectiveThis study aimed to determine the change in use and cost-effectiveness of prenatal aneuploidy serum screening in a low-risk Hispanic Medicaid population in Massachusetts. STUDY

designWe conducted a retrospective chart review of Spanish-speaking pregnant patients younger than 35 years of age who underwent aneuploidy serum screening at a Massachusetts community health center. The study compared the aneuploidy serum screening rates for the periods before and after May 2016 when the Massachusetts Medicaid program, MassHealth, temporarily discontinued reimbursement for the screening. Based on these rates, we developed a Markov cohort simulation model to assess the economic value of reimbursed aneuploidy screening vs nonreimbursed or limited screening. Clinical outcomes included trisomy 21, live births, and therapeutic abortions for a trisomy 21 diagnosis. Economic outcomes included discounted quality-adjusted life years and lifetime medical costs, net health benefit, and incremental cost-effectiveness ratios.

resultsBefore the MassHealth policy change, 69% (55/80) of pregnant individuals selected quad or sequential screens in comparison with only 9% (10/112) who selected screens after the policy change. Traditional aneuploidy serum screening in a low-risk (aged <35 years) Hispanic population was considered to be cost-saving (ie, led to lower incremental costs and higher incremental benefits when compared with nonreimbursed or limited screening).

conclusionFrom a United States healthcare payer perspective, aneuploidy serum screening for Hispanic pregnant individuals under 35 years of age is economically advantageous when compared with limited screening

Indexed as

aneuploidy screeningcommunity health centercost-effectivenessICD-10low-risk pregnancyMedicaidprice elasticitypublic payerserum screeningtrisomy 21

Identifiers

PMID38205132
PMCPMC10777109
OpenAlexW4388792689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.