Evidence map›Paper›PMID 38205098›Full record

ReviewPulmonary circulation2024

Pulmonary hypertension in the setting of interstitial lung disease: Approach to management and treatment. A consensus statement from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative-Group 3 Pulmonary Hypertension.

Oksana A Shlobin, Eric Shen, Stephen J Wort, Lucilla Piccari, John A Scandurra, Paul M Hassoun, Sylvia M Nikkho, Steven D Nathan

Open access · goldAbstract readReview
In one paragraph

Review in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 20 citations in OpenAlex.

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  19. Pulmonary hypertension associated with lung diseases.The European respiratory journal · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Oksana A ShlobinAdvanced Lung Disease and Transplant Program Inova Health System Falls Church Virginia USA.ORCID 0000-0003-4131-8499
Eric ShenUnited Therapeutics Corporation Research Triangle Park North Carolina USA.ORCID 0000-0001-5621-6570
Stephen J WortNational Heart and Lung Institute Imperial College London London UK.ORCID https://orcid.org/0000-0003-4287-1173
Lucilla PiccariDepartment of Pulmonary Medicine Hospital del Mar Barcelona Spain.ORCID 0000-0002-2241-7523
John A ScandurraAria CV Inc. St. Paul Minnesota USA.
Paul M HassounDepartment of Medicine, Division of Pulmonary and Critical Care Medicine Johns Hopkins University Baltimore Maryland USA.ORCID 0000-0003-0601-4975
Sylvia M NikkhoGlobal Clinical Development Bayer AG Berlin Germany.ORCID 0000-0003-1245-2656
Steven D NathanAdvanced Lung Disease and Transplant Program Inova Health System Falls Church Virginia USA.ORCID 0000-0002-6270-1617
Inova Health System · USBayer (Germany) · DECereal Disease Laboratory · USHospital Del Mar · ESImperial College London · GBJohns Hopkins University · USTriangle · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) due to interstitial lung disease (ILD), a commonly encountered complication of fibrotic ILDs, is associated with significant morbidity and mortality. Until recently, the studies of pulmonary vasodilator therapy in PH-ILD have been largely disappointing, with some even demonstrating the potential for harm. This paper is part of a series of Consensus Statements from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative for Group 3 Pulmonary Hypertension, with prior publications covering pathogenesis, prevalence, clinical features, phenotyping, clinical trials, and impact of PH-ILD. It offers a comprehensive review of and a holistic approach to treatment of PH-ILD, including the management of underlying interstitial lung diseases, importance of treating the comorbidities, emphasis on importance of exercise and palliation of dyspnea, and review of the most up-to-date guidelines for referral for potential lung transplant work up. It also summarizes the prior, ongoing, and possibly future studies in treatment of the vascular derangement of this morbid condition.

Indexed as

idiopathic pulmonary fibrosismanagementparenchymal lung diseasepulmonary vascular disease

Identifiers

PMID38205098
PMCPMC10777777
OpenAlexW4390702534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.