Evidence map›Paper›PMID 38205016›Full record

ArticleJACC. CardioOncology2023

Cancer-Associated Thrombosis: Trends in Clinical Features, Treatment, and Outcomes From 2001 to 2020.

Laurent Bertoletti, Olga Madridano, David Jiménez, Alfonso Muriel, Behnood Bikdeli, Cihan Ay, Javier Trujillo-Santos, Marijan Bosevski, Patricia Sigüenza, Manuel Monreal

Registry-linked trialAbstract read
In one paragraph

Article in JACC. CardioOncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02832245 (Computerized Registry of Patients With Venous Thromboembolism), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02832245 recruitingnot on this map

Computerized Registry of Patients With Venous Thromboembolism (RIETE)

Typeobservational_patient_registrySponsorManuel MonrealRan2001 to 2027Enrolled120,000ConditionsVenous Thromboembolism
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Causes of death after surgery among cancer patients: a population-based cohort study.International journal of surgery (London, England) · 2026
    Article
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  10. Article
  11. Article
  12. Review
  13. Review
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  19. Sex-specific Risks in Lung Cancer-Associated Thrombosis: Focus on Female Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
  20. Venous Thromboembolism in Women with Breast and Gynaecological Cancers: What Do We Know and What Should We Do?Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laurent BertolettiService de Médecine Vasculaire et Thérapeutique, Centre Hospitalier Universitaire de St-Etienne, Saint-Etienne, France.
Olga MadridanoDepartment of Internal Medicine, Hospital Infanta Sofía, Madrid, Spain.
David JiménezRespiratory Department, Hospital Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
Alfonso MurielBiostatistics Unit, Ramón y Cajal Hospital IRYCIS, CIBERESP, Nursing and Physiotherapy Department, University of Alcala, Madrid, Spain.
Behnood BikdeliCardiovascular Medicine Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Cihan AyDepartment of Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria.
Javier Trujillo-SantosInternal Medicine Department, Hospital Universitario Santa Lucía, Complejo Hospitalario Universitario de Cartagena, Murcia, Spain.
Marijan BosevskiUniversity Cardiology Clinic Faculty of Medicine, Skopje, North Macedonia.
Patricia SigüenzaDepartment of Internal Medicine, Hospital Germans Trias I Pujol, Badalona, Barcelona, Spain.
Manuel MonrealFaculty of Health Sciences, Universidad Católica San Antonio de Murcia, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite advances in cancer and venous thromboembolism (VTE) management, the epidemiology of cancer-associated thrombosis management over time remains unclear. Objectives: We analyzed data from the RIETE (Registro Informatizado de la Enfermedad Trombo Embólica) registry spanning 2001 to 2020 to investigate temporal trends in clinical characteristics and treatments for cancer-associated thrombosis. Methods: Using multivariable survival regression, we examined temporal trends in risk-adjusted rates of symptomatic VTE recurrences, major bleeding, and death within 30 days after incident VTE. Results: Among the 17,271 patients with cancer-associated thrombosis, there was a progressive increase in patients presenting with pulmonary embolism (from 44% in 2001-2005 to 55% in 2016-2020; Conclusions: In this multicenter study of cancer patients with VTE, there was a decline in thrombotic, hemorrhagic, and fatal events from 2001 to 2020. (Registro Informatizado de la Enfermedad Trombo Embólica [RIETE]; NCT02832245).

Indexed as

anticoagulantbleedingcancersurvivalthrombosis

Identifiers

PMID38205016
PMCPMC10774792

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.