Evidence map›Paper›PMID 38205002›Full record

ArticleJACC. CardioOncology2023

Cardiovascular Events After Hematopoietic Stem Cell Transplant: Incidence and Risk Factors.

Alexi Vasbinder, Christopher W Hoeger, Tonimarie Catalan, Elizabeth Anderson, Catherine Chu, Megan Kotzin, Jeffrey Xie, Rayan Kaakati, Hanna P Berlin, Husam Shadid and 21 more

Open access · goldAbstract read
In one paragraph

Article in JACC. CardioOncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Dyslipidaemias in cancer patients.European heart journal · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 4 institutions in 1 country.

Alexi VasbinderDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Christopher W HoegerDivision of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Tonimarie CatalanDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Elizabeth AndersonDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Catherine ChuRush Medical College, Rush University, Chicago, Illinois, USA.
Megan KotzinRush Medical College, Rush University, Chicago, Illinois, USA.
Jeffrey XieDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Rayan KaakatiDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Hanna P BerlinDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Husam ShadidDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Daniel PerryDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Michael PanDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Radhika TakiarDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Kishan PadaliaDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Jamie MillsDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Chelsea MelocheDivision of Cardiovascular Medicine, Texas Heart Institute, Houston, Texas, USA.
Alina BardwellDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Matthew RochlenDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Pennelope BlakelyDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Monika LejaDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Mousumi BanerjeeDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Mary RiwesDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
John MagenauDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Sarah AnandDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Monalisa GhoshDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Attaphol PawarodeDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Gregory YanikDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Sunita NathanDivision of Hematology, Oncology and Cell Therapy, Department of Internal Medicine, Rush Medical College, Chicago, Illinois, USA.
John MaciejewskiDivision of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Tochukwu OkwuosaDivision of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Salim S HayekDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan · USMichigan Medicine · USRush University Medical Center · USBeth Israel Deaconess Medical Center · US

Funding

TRAINING IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007853 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David J. Pinsky · 1996 to 2026
$11.6M
NHLBI NIH HHS T32 HL007853
6 · The paper itself

Abstract

Background: Hematopoietic stem cell transplantation (HSCT) is associated with various cardiovascular (CV) complications. Objectives: We sought to characterize the incidence and risk factors for short-term and long-term CV events in a contemporary cohort of adult HSCT recipients. Methods: We conducted a multicenter observational study of adult patients who underwent autologous or allogeneic HSCT between 2008 and 2019. Data on demographics, clinical characteristics, conditioning regimen, and CV outcomes were collected through chart review. CV outcomes were a composite of CV death, myocardial infarction, heart failure, atrial fibrillation/flutter, stroke, and sustained ventricular tachycardia and were classified as short-term (≤100 days post-HSCT) or long-term (>100 days post-HSCT). Results: In 3,354 patients (mean age 55 years; 40.9% female; 30.1% Black) followed for a median time of 2.3 years (Q1-Q3: 1.0-5.4 years), the 100-day and 5-year cumulative incidences of CV events were 4.1% and 13.9%, respectively. Atrial fibrillation/flutter was the most common short- and long-term CV event, with a 100-day incidence of 2.6% and a 5-year incidence of 6.8% followed by heart failure (1.1% at 100 days and 5.4% at 5 years). Allogeneic recipients had a higher incidence of long-term CV events compared to autologous recipients (5-year incidence 16.4% vs 12.1%; Conclusions: The incidence of short-term CV events in HSCT recipients is relatively low. Long-term events were more common among allogeneic recipients and those with pre-existing CV comorbidities.

Indexed as

atrial fibrillationbone marrow transplantcardiovascular diseaseheart failurehematopoietic stem cell transplantrisk factor

Identifiers

PMID38205002
PMCPMC10774793
OpenAlexW4386865788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.