Evidence map›Paper›PMID 38204712›Full record

ArticleJTCVS open2023

Conditional survival analysis of patients with resected non-small cell lung cancer.

Talib Chaudhry, Vaishnavi Krishnan, Andrew E Donaldson, Zachary M Palmisano, Sanjib Basu, Nicole M Geissen, Justin M Karush, Gillian C Alex, Jeffrey A Borgia, Michael J Liptay and 1 more

Abstract read
In one paragraph

Article in JTCVS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Talib ChaudhryDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Vaishnavi KrishnanDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Andrew E DonaldsonDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Zachary M PalmisanoDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Sanjib BasuDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Nicole M GeissenDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Justin M KarushDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Gillian C AlexDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Jeffrey A BorgiaDepartment of Pathology, Rush University Medical Center, Chicago, Ill.
Michael J LiptayDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.
Christopher W SederDepartment of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Ill.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conditional survival (CS) analyses provide an estimate of survival accounting for years already survived after treatment. We aim to evaluate the difference between actuarial and conditional survival in patients following lung resection for non-small cell lung cancer (NSCLC). In addition, CS analyses are used to examine whether prognosticators of survival change over time following surgery. Methods: Patients who underwent anatomic lung resection at a single institution for pathologic stage I-IIIA NSCLC between 2010 and 2021 were identified; those who underwent wedge resection for node-negative tumors ≤2 cm were also included. CS estimates were calculated as the probability of remaining disease-free after Results: Overall, 863 patients met the study inclusion criteria, with a median follow-up of 44.1 months. Conditional overall survival (OS) and disease-free survival (DFS) were greater than actuarial rates at all time points after surgery. At the time of resection, male sex (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.03 to 1.72; Conclusions: Conditional survival analyses provide dynamic assessments of OS and DFS after NSCLC resection. After 3 years without recurrence, certain characteristics associated with DFS at the time of surgery no longer prognosticate recurrence.

Indexed as

conditional survivaldisease-free survivalnon–small cell lung cancerprognosis

Identifiers

PMID38204712
PMCPMC10775048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.