Evidence map›Paper›PMID 38204470›Full record

ArticleAsian journal of pharmaceutical sciences2023

Unleashing the healing potential: Exploring next-generation regenerative protein nanoscaffolds for burn wound recovery.

Liangwei Si, Xiong Guo, Hriday Bera, Yang Chen, Fangfang Xiu, Peixin Liu, Chunwei Zhao, Yasir Faraz Abbasi, Xing Tang, Vito Foderà and 2 more

Abstract read
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Liangwei SiWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Xiong GuoWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Hriday BeraWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Yang ChenWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Fangfang XiuWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Peixin LiuWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Chunwei ZhaoWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Yasir Faraz AbbasiWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Xing TangDepartment of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Vito FoderàDepartment of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen O, Denmark.
Dongmei CunWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.
Mingshi YangWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang l10016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn injury is a serious public health problem and scientists are continuously aiming to develop promising biomimetic dressings for effective burn wound management. In this study, a greater efficacy in burn wound healing and the associated mechanisms of α-lactalbumin (ALA) based electrospun nanofibrous scaffolds (ENs) as compared to other regenerative protein scaffolds were established. Bovine serum albumin (BSA), collagen type I (COL), lysozyme (LZM) and ALA were separately blended with poly(ε-caprolactone) (PCL) to fabricate four different composite ENs (LZM/PCL, BSA/PCL, COL/PCL and ALA/PCL ENs). The hydrophilic composite scaffolds exhibited an enhanced wettability and variable mechanical properties. The ALA/PCL ENs demonstrated higher levels of fibroblast proliferation and adhesion than the other composite ENs. As compared to PCL ENs and other composite scaffolds, the ALA/PCL ENs also promoted a better maturity of the regenerative skin tissues and showed a comparable wound healing effect to Collagen sponge

Indexed as

ElectrospinningNanofibrous dressingRegenerative proteinsSerotoninThird-degree burnα-lactalbumin

Identifiers

PMID38204470
PMCPMC10777420

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.