Evidence map›Paper›PMID 38204456›Full record

ArticleClinical, cosmetic and investigational dermatology2024

Abrocitinib as a Novel Treatment for Multiple Skin Disorders: 3 Case Reports and a Scoping Review.

Pingjiao Chen, Jingyao Liang, Changxing Li, Qian Li, Wenyan Liu, Junhui Zhu, Weifeng Chen, Xibao Zhang

Open access · goldAbstract readCase ReportsScoping Review
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Pingjiao Chen *Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Jingyao Liang *Institute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Changxing LiDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Qian LiInstitute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Wenyan LiuInstitute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Junhui ZhuInstitute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Weifeng ChenInstitute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Xibao ZhangInstitute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People's Republic of China.
Guangzhou Institute of Dermatology · CNSouthern Medical University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Janus kinase (JAK) inhibitors are increasingly being used in dermatology due to their broad potential in managing both local and systemic inflammation. More recently, abrocitinib, an oral JAK 1 inhibitor, has shown promising clinical efficacy in the treatment of various skin disorders beyond moderate to severe atopic dermatitis (AD). We firstly presented three cases, each with diagnosis of pyoderma gangrenosum (PG), livedoid vasculopathy (LV), or hidradenitis suppurativa (HS), and conducted a comprehensive scoping review of the available literature on the use of abrocitinib in the treatment of diverse skin disorders. We summarized a total of 16 skin disorders, including our cases. The results indicated that abrocitinib, whether used as monotherapy or in combination with other treatments, was effective and well-tolerated in these disorders. These findings expanded the range of diseases for which abrocitinib may serve as an alternative therapeutic choice.

Indexed as

abrocitinibatopic dermatitishidradenitis suppurativaJAK inhibitorslivedoid vasculopathypyoderma gangrenosum

Identifiers

PMID38204456
PMCPMC10778201
OpenAlexW4390607611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.