Evidence map›Paper›PMID 38204399›Full record

SynthesisPharmacology research & perspectives2024

A systematic review on experimental studies about patient adherence to treatment.

Frans Folkvord, Ana Roca-Umbert Würth, Karlijn van Houten, Aad R Liefveld, Jim Ingebretsen Carlson, Nadine Bol, Emiel Krahmer, Gwenn Beets, Rachel Drbohlav Ollerton, Eva Turk and 16 more

Abstract readSystematic Review
In one paragraph

Synthesis in Pharmacology research & perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Frans FolkvordPredictBy, Barcelona, Spain.ORCID https://orcid.org/0000-0001-7602-3792
Ana Roca-Umbert WürthPredictBy, Barcelona, Spain.
Karlijn van HoutenPredictBy, Barcelona, Spain.
Aad R LiefveldLink2Trials, Hilversum, The Netherlands.
Jim Ingebretsen CarlsonPredictBy, Barcelona, Spain.
Nadine BolTilburg Center for Cognition and Communication (TiCC), Department of Communication and Cognition, Tilburg University, Tilburg, The Netherlands.
Emiel KrahmerTilburg Center for Cognition and Communication (TiCC), Department of Communication and Cognition, Tilburg University, Tilburg, The Netherlands.
Gwenn BeetsTilburg Center for Cognition and Communication (TiCC), Department of Communication and Cognition, Tilburg University, Tilburg, The Netherlands.
Rachel Drbohlav OllertonTilburg Center for Cognition and Communication (TiCC), Department of Communication and Cognition, Tilburg University, Tilburg, The Netherlands.
Eva TurkInstitute for Health and Society, University of Oslo, Oslo, Norway.
Harald Hrubos-StrømAkershus University Hospital, Lørenskog, Norway.
Hamza NahouiAkershus University Hospital, Lørenskog, Norway.
Gunnar EinvikAkershus University Hospital, Lørenskog, Norway.
Henrik SchirmerAkershus University Hospital, Lørenskog, Norway.
Anne MoenInstitute for Health and Society, University of Oslo, Oslo, Norway.
Jaime Barrio-CortesFoundation for Biosanitary Research and Innovation in Primary Care, Madrid, Spain.ORCID https://orcid.org/0000-0002-2582-0203
Beatriz Merino-BarbanchoUniversidad Politécnica de Madrid, Life Supporting Technologies Research Group, Madrid, Spain.
Peña ArroyoUniversidad Politécnica de Madrid, Life Supporting Technologies Research Group, Madrid, Spain.
Giuseppe FicoUniversidad Politécnica de Madrid, Life Supporting Technologies Research Group, Madrid, Spain.
Luís MidãoAssociate Laboratory i4HB - Institute for Health and Bioeconomy, UCIBIO - Applied Molecular Biosciences Unit, Porto4Ageing - Competence Centre on Active and Healthy Ageing, Faculty of Pharmacy of the University of Porto, Porto, Portugal.
Rute SampaioCINTESIS@RISE, Department of Biomedicine, Faculty of Medicine of the University of Porto, Porto, Portugal.
João A FonsecaMEDIDA, Medicina, EDucação, I&D e Avaliação Lda, Portugal.
Katja GeipelDepartment of Otorhinolaryngology, Heinrich-Heine-University, Düsseldorf, Germany.
Kathrin ScheckenbachDepartment of Otorhinolaryngology, Heinrich-Heine-University, Düsseldorf, Germany.
Laura E de RuiterBehavioral Science Consortium, Astellas Pharma, Northbrook, Illinois, USA.
Francisco Lupiáñez-VillanuevaPredictBy, Barcelona, Spain.

Funding

IHIInnovative Health Initiative 101034369
6 · The paper itself

Abstract

A better understanding of patients' adherence to treatment is a prerequisite to maximize the benefit of healthcare provision for patients, reduce treatment costs, and is a key factor in a variety of subsequent health outcomes. We aim to understand the state of the art of scientific evidence about which factors influence patients' adherence to treatment. A systematic literature review was conducted using PRISMA guidelines in five separate electronic databases of scientific publications: PubMed, PsycINFO (ProQuest), Cochrane library (Ovid), Google Scholar, and Web of Science. The search focused on literature reporting the significance of factors in adherence to treatment between 2011 and 2021, including only experimental studies (e.g., randomized controlled trials [RCT], clinical trials, etc.). We included 47 experimental studies. The results of the systematic review (SR) are grouped according to predetermined categories of the World Health Organization (WHO): socioeconomic, treatment, condition, personal, and healthcare-related factors. This review gives an actual overview of evidence-based studies on adherence and analyzed the significance of factors defined by the WHO classification. By showing the strength of certain factors in several independent studies and concomitantly uncovering gaps in research, these insights could serve as a basis for the design of future adherence studies and models.

Indexed as

Health Care CostsPatient ComplianceDatabases, FactualHumansWorld Health Organizationdimensionsexperimental studiesfactorsmedicationpatient adherencesystematic review

Identifiers

PMID38204399
PMCPMC10782217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.