Evidence map›Paper›PMID 38204361›Full record

ArticleCancer medicine2024

An analysis of the relationship of triglyceride glucose index with gastric cancer prognosis: A retrospective study.

Chao Cai, Cheng Chen, Xiuli Lin, Huihui Zhang, Mingming Shi, Xiaolei Chen, Weisheng Chen, Didi Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chao CaiDepartment of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Hepatology Institute of Wenzhou Medical University, Wenzhou Key Laboratory of Hepatology, Zhejiang, China.
Cheng ChenDepartment of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Hepatology Institute of Wenzhou Medical University, Wenzhou Key Laboratory of Hepatology, Zhejiang, China.
Xiuli LinDepartment of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Hepatology Institute of Wenzhou Medical University, Wenzhou Key Laboratory of Hepatology, Zhejiang, China.
Huihui ZhangDepartment of Gastrointestinal Surgery, National Key Clinical Specialty(General Surgery), The First Affiliated Hospital Of Wenzhou Medical University, Zhejiang, China.
Mingming ShiDepartment of Hepatobiliary Surgery, Affiliated Yueqing Hospital of Wenzhou Medical University.
Xiaolei ChenDepartment of Gastrointestinal Surgery, National Key Clinical Specialty(General Surgery), The First Affiliated Hospital Of Wenzhou Medical University, Zhejiang, China.
Weisheng ChenDepartment of Gastrointestinal Surgery, National Key Clinical Specialty(General Surgery), The First Affiliated Hospital Of Wenzhou Medical University, Zhejiang, China.
Didi ChenDepartment of Radiation Oncology, The First Affiliated Hospital, Wenzhou Medical University, Zhejiang, China.ORCID 0009-0002-1517-5543
Wenzhou Medical University · CN

Funding

General Project of Education Department of Zhejiang Province Y202353447National Key Clinical Specialty (General Surgery), The First Affiliated Hospital Of Wenzhou Medical University. Wenzhou Science and Technology Plan Project Y2020123; Y2023111Zhejiang Medical and Health Science and Technology Program 2024KY139
6 · The paper itself

Abstract

AIMS/

introductionGastric cancer, one of the most common malignant tumors worldwide, is affected by insulin resistance. The triglyceride glucose (TYG) index is considered a surrogate indicator of insulin resistance; however, its prognostic value in patients with gastric cancer remains obscure. This study aimed to determine whether the TYG index could predict the long-term prognosis of patients with gastric cancer after radical resection gastrectomy. MATERIALS AND

methodsWe retrospectively analyzed patients with gastric cancer who underwent radical resection gastrectomy. The preoperative TYG index was calculated using the patients' laboratory data. Patients were divided into two groups based on a high or low TYG index. We observed overall survival and evaluated the clinical application value of the index using Cox proportional hazards regression to calculate independent parameters. A prediction model was also established.

resultsIn total, 822 patients with gastric cancer were included. The high and low TYG index groups comprised 353 and 469 patients, respectively. The overall survival time was significantly longer in the high-index group than in the low-index group. In the multivariate analysis, TYG index, preoperative age, surgical procedure, tumor node metastasis (TNM) stage, N stage, and postoperative complications (all p < 0.01) were considered independent prognostic predictors. Based on the multivariate analysis, the riglyceride glucose (TYG) index hazard ratio was 0.70 (95% confidence interval, 0.54-0.89, p = 0.004).

conclusionsWe established a model with a high clinical application value and clinical practice relevance to predict the prognosis of gastric cancer. In this model, TYG was an independent protective factor for gastric cancer prognosis.

Indexed as

Insulin ResistanceStomach NeoplasmsGlucoseHumansRetrospective StudiesTriglyceridesGlucoseTriglyceridesgastric cancerinsulin resistanceprognosis predictiontriglyceride glucose index

Identifiers

PMID38204361
PMCPMC10905246
OpenAlexW4390743266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.