Evidence map›Paper›PMID 38204337›Full record

ArticleThe oncologist2024

Sequential Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor-Induced Radical Surgery in Oligometastatic Non-Small Cell Lung Cancer: A Case Report.

Huaiyu Wang, Zaiwen Fan, Xiaoming Yang, Qing Wu, Suxin Jiang, Jingna Zhu, Jie Liu, Chuanhong Zhou, Yinghui Liu, Xia You and 1 more

Abstract readCase Reports
In one paragraph

Article in The oncologist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huaiyu WangThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Zaiwen FanMedical Oncology Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Xiaoming YangAnesthesiology Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Qing WuThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Suxin JiangThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Jingna ZhuThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Jie LiuThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Chuanhong ZhouThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Yinghui LiuThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Xia YouThe State Key Lab of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing, Jiangsu Province, People's Republic of China.
Yong HanThoracic Surgery Department, Air Force Medical Center, PLA, Beijing, People's Republic of China.

Funding

Wu Jieping Medical Foundation 320.6750.2020-19-15
6 · The paper itself

Abstract

Sequential regimens in patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) can overcome tyrosine kinase inhibitor (TKI) resistance and maximize clinical benefit. Patients with advanced NSCLC can achieve excellent tumor control after a period of EGFR-TKI treatment. Patients may benefit from additional local treatment, such as surgery or radiation therapy, once the tumor is under control. Here, we present a case of a patient with advanced oligometastatic NSCLC with EGFR mutations who achieved downstaging through sequential EGFR-TKI-based precision medicine allowing resection of residual disease.

Indexed as

Carcinoma, Non-Small-Cell LungErbB ReceptorsLung NeoplasmsProtein Kinase InhibitorsAgedFemaleHumansMaleMiddle AgedMutationNeoplasm MetastasisTyrosine Kinase InhibitorsEGFR protein, humanErbB ReceptorsProtein Kinase InhibitorsTyrosine Kinase InhibitorsdownstagingEGFR L718Qoligometastatic NSCLCwhole course medical management

Identifiers

PMID38204337
PMCPMC11144966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.