Evidence map›Paper›PMID 38204146›Full record

ReviewClinical & experimental ophthalmology2024

How does ocular graft-versus-host disease fit under the dry eye umbrella? A review.

Nicole B Kantor, Arianna Tovar, Trent Wang, Anat Galor

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical & experimental ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Nicole B KantorBascom Palmer Eye Institute, University of Miami, Miami, Florida, USA.
Arianna TovarDepartment of Ophthalmology, Wellstar MCG Health, Augusta, Georgia, USA.
Trent WangDivision of Transplantation and Cellular Therapy, Sylvester Comprehensive Cancer Center, Adult Stem Cell Transplant Program, University of Miami Hospital and Clinics, Miami, Florida, USA.
Anat GalorBascom Palmer Eye Institute, University of Miami, Miami, Florida, USA.ORCID 0000-0002-3026-6155
University of Miami · USUniversity of Miami Hospital · USWellStar Health System · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Abigail S Hackam · 2004 to 2026
$12.2M
UM Calabresi Clinical Oncology Research Career Development AwardK12CA226330 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Alan Pollack · 2018 to 2026
$5.1M
Differentiation of Clinical Phenotypes of Inflammatory and Neuropathic Ocular Pain Conditions with Morphologic Measures and Functional Brain ImagingU01EY034686 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Eric Alan Moulton · 2022 to 2026
$4.7M
Defining bacterial members of the ocular surface microbiome and assessing stability over timeU24EY035102 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GALOR, ANAT, ST LEGER, ANTHONY J · 2023 to 2025
$3.3M
Tear protein biomarkers of refractive surgery painR33EY032468 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI AICHER, SUE A, GALOR, ANAT · 2023 to 2025
$2.9M
A pilot study of the safety and feasibility of transcutaneous electrical nerve stimulation (TENS) for chronic ocular painI21RX003883 · VA · MIAMI VA HEALTH CARE SYSTEM · PI FELIX, ELIZABETH ROY · 2022 to 2023
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Neural mechanisms underlying photophobia and dry eyeI01CX002015 · VA · MIAMI VA HEALTH CARE SYSTEM · PI Anat Galor · 2020 to 2026
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Lipid mediators and their signaling in ocular surface inflammation and meibomian gland dysfunctionI01BX004893 · VA · MIAMI VA HEALTH CARE SYSTEM · PI GALOR, ANAT, MANDAL, NAWAJES · 2021 to 2025
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BLRD VA I01 BX004893CSRD VA I01 CX002015NCI NIH HHS K12 CA226330NEI NIH HHS P30 EY014801NEI NIH HHS R33 EY032468NEI NIH HHS U01 EY034686NEI NIH HHS U24 EY035102NEI NIH HHS U24EY035102RRD VA I21 RX003883
6 · The paper itself

Abstract

Graft-versus-host disease (GVHD) is a systemic disease that can affect multiple organs as a consequence of an allogeneic haematopoietic stem cell transplant. One organ system that is often affected in GVHD is the eyes. Ocular GVHD (oGVHD) may involve various structures within the eye including the lacrimal glands, eyelids, conjunctiva, cornea, and nasolacrimal ducts, and is a source of morbidity in patients with GVHD. Common presenting features of GVHD overlap with dry eye disease (DED), including decreased tear production, epithelial disruption, and Meibomian gland dysfunction (MGD). In this review, we aim to compare oGVHD and DED to better understand the similarities and differences between the conditions, with a focus on pathophysiology, risk factors, clinical features, and treatments.

Indexed as

Dry Eye SyndromesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationMeibomian Gland DysfunctionConjunctivaCorneaHumansacuteaqueous tear deficiencychronicdry eye diseaseocular graft-versus-host disease

Identifiers

PMID38204146
PMCPMC10939887
OpenAlexW4390744237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.