Evidence map›Paper›PMID 38204023›Full record

ArticleMaterials (Basel, Switzerland)2023

Low-Temperature Plasmas Improving Chemical and Cellular Properties of Poly (Ether Ether Ketone) Biomaterial for Biomineralization.

John P Bradford, Gerardo Hernandez-Moreno, Renjith R Pillai, Alexandria L Hernandez-Nichols, Vinoy Thomas

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Synthesis of Heterostructured TiOMaterials (Basel, Switzerland) · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

John P BradfordPolymer and Healthcare Material/Devices, Department of Mechanical and Materials Engineering, The University of Alabama, Birmingham, AL 35294, USA.
Gerardo Hernandez-MorenoPolymer and Healthcare Material/Devices, Department of Mechanical and Materials Engineering, The University of Alabama, Birmingham, AL 35294, USA.ORCID 0000-0002-8033-9615
Renjith R PillaiPolymer and Healthcare Material/Devices, Department of Mechanical and Materials Engineering, The University of Alabama, Birmingham, AL 35294, USA.ORCID 0000-0003-0677-005X
Alexandria L Hernandez-NicholsDepartment of Cellular and Molecular Pathology, Heersink School of Medicine, The University of Alabama, Birmingham, AL 35294, USA.
Vinoy ThomasPolymer and Healthcare Material/Devices, Department of Mechanical and Materials Engineering, The University of Alabama, Birmingham, AL 35294, USA.ORCID 0000-0002-1191-3353
University of Alabama · US

Funding

Redox Signaling in the Endoplasmic Reticulum Regulates Endothelial Surface N-glycoforms: implications for vascular inflammationF31HL156601 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HERNANDEZ-NICHOLS, ALEXANDRIA · 2022 to 2023
$81k
NHLBI NIH HHS F31 HL156601
6 · The paper itself

Abstract

Osteoblastic and chemical responses to Poly (ether ether ketone) (PEEK) material have been improved using a variety of low-temperature plasmas (LTPs). Surface chemical properties are modified, and can be used, using low-temperature plasma (LTP) treatments which change surface functional groups. These functional groups increase biomineralization, in simulated body fluid conditions, and cellular viability. PEEK scaffolds were treated, with a variety of LTPs, incubated in simulated body fluids, and then analyzed using multiple techniques. First, scanning electron microscopy (SEM) showed morphological changes in the biomineralization for all samples. Calcein staining, Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS) confirmed that all low-temperature plasma-treated groups showed higher levels of biomineralization than the control group. MTT cell viability assays showed LTP-treated groups had increased cell viability in comparison to non-LTP-treated controls. PEEK treated with triethyl phosphate plasma (TEP) showed higher levels of cellular viability at 82.91% ± 5.00 (

Indexed as

bioactive surfacebiomineralizationbone implantPEEKplasma modification

Identifiers

PMID38204023
PMCPMC10780010
OpenAlexW4390347285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.