Evidence map›Paper›PMID 38203848›Full record

ArticleInternational journal of molecular sciences2024

A Million-Cow Validation of a Chromosome 14 Region Interacting with All Chromosomes for Fat Percentage in U.S. Holstein Cows.

Dzianis Prakapenka, Zuoxiang Liang, Hafedh B Zaabza, Paul M VanRaden, Curtis P Van Tassell, Yang Da

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Large-Sample Genomic Data Mining for Quantitative Traits in U.S. Holstein Cows.Journal of data mining in genomics & proteomics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dzianis PrakapenkaDepartment of Animal Science, University of Minnesota, Saint Paul, MN 55108, USA.ORCID 0000-0002-4592-7120
Zuoxiang LiangDepartment of Animal Science, University of Minnesota, Saint Paul, MN 55108, USA.ORCID 0000-0002-9058-9327
Hafedh B ZaabzaAnimal Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD 20705, USA.
Paul M VanRadenAnimal Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD 20705, USA.ORCID 0000-0002-9123-7278
Curtis P Van TassellAnimal Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD 20705, USA.ORCID 0000-0002-8416-2087
Yang DaDepartment of Animal Science, University of Minnesota, Saint Paul, MN 55108, USA.
Agricultural Research Service · USUniversity of Minnesota · US

Funding

Genomic discovery and prediction for quantitative traits with complex genetic mechanismsR01HG012425 · NHGRI · UNIVERSITY OF MINNESOTA · PI DA, YANG · 2022 to 2024
$729k
NHGRI NIH HHS R01 HG012425NIH HHS R01HG012425
6 · The paper itself

Abstract

A genome-wide association study (GWAS) of fat percentage (FPC) using 1,231,898 first lactation cows and 75,198 SNPs confirmed a previous result that a Chr14 region about 9.38 Mb in size (0.14-9.52 Mb) had significant inter-chromosome additive × additive (A×A) effects with all chromosomes and revealed many new such effects. This study divides this 9.38 Mb region into two sub-regions, Chr14a at 0.14-0.88 Mb (0.74 Mb in size) with 78% and Chr14b at 2.21-9.52 Mb (7.31 Mb in size) with 22% of the 2761 significant A×A effects. These two sub-regions were separated by a 1.3 Mb gap at 0.9-2.2 Mb without significant inter-chromosome A×A effects. The

Indexed as

Chromosomes, Human, Pair 14Genome-Wide Association StudyAnimalsCattleFemaleFertilityHumansLactationNF-kappa BPhenotypePoly(ADP-ribose) PolymerasesProto-Oncogene ProteinsNF-kappa BPARP10 protein, humanPoly(ADP-ribose) PolymerasesProto-Oncogene ProteinsTONSL protein, humancowepistasisfat percentageGWASHolsteinSNP

Identifiers

PMID38203848
PMCPMC10779465
OpenAlexW4390579742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.