Evidence map›Paper›PMID 38203833›Full record

ArticleInternational journal of molecular sciences2024

Identification of Muscle Strength-Related Gut Microbes through Human Fecal Microbiome Transplantation.

Ji-Seon Ahn, Bon-Chul Koo, Yu-Jin Choi, Woon-Won Jung, Hyun-Sook Kim, Suk-Jun Lee, Seong-Tshool Hong, Hea-Jong Chung

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ji-Seon AhnGwangju Center, Korea Basic Science Institute, Gwangju 61751, Jeolla, Republic of Korea.ORCID 0000-0001-9465-2517
Bon-Chul KooDivision of Bioconvergence Analysis, Korea Basic Science Institute, Ochang 28119, Chungbuk, Republic of Korea.
Yu-Jin ChoiGwangju Center, Korea Basic Science Institute, Gwangju 61751, Jeolla, Republic of Korea.
Woon-Won JungDepartment of Biomedical Laboratory Science, Cheongju University, Cheongju 28503, Chungbuk, Republic of Korea.
Hyun-Sook KimDepartment of Biomedical Laboratory Science, Cheongju University, Cheongju 28503, Chungbuk, Republic of Korea.
Suk-Jun LeeDepartment of Biomedical Laboratory Science, Cheongju University, Cheongju 28503, Chungbuk, Republic of Korea.
Seong-Tshool HongDepartment of Biomedical Sciences and Institute for Medical Science, Jeonbuk National University Medical School, Jeonju 54907, Jeonbuk, Republic of Korea.ORCID 0000-0001-8254-6581
Hea-Jong ChungGwangju Center, Korea Basic Science Institute, Gwangju 61751, Jeolla, Republic of Korea.ORCID 0000-0002-1185-7654
Cheongju University · KRKorea Basic Science Institute · KRJeonbuk National University · KR

Funding

Korea Basic Science Institute C320000Korea Basic Science Institute C330340Korea Basic Science Institute C380300Korea Health Industry Development Institute HV22C0171National Research Foundation of Korea RS-2023-00224099
6 · The paper itself

Abstract

The gut microbiome is well known for its influence on human physiology and aging. Therefore, we speculate that the gut microbiome may affect muscle strength in the same way as the host's own genes. To demonstrate candidates for gut microbes affecting muscle strength, we remodeled the original gut microbiome of mice into human intestinal microbiome through fecal microbiome transplantation (FMT), using human feces and compared the changes in muscle strength in the same mice before and three months after FMT. After comparing before and after FMT, the mice were divided into three groups based on the observed changes in muscle strength: positive, none, and negative changes in muscle strength. As a result of analyzing the α-diversity, β-diversity, and co-occurrence network of the intestinal microbial community before and after FMT, it was observed that a more diverse intestinal microbial community was established after FMT in all groups. In particular, the group with increased muscle strength had more gut microbiome species and communities than the other groups. Fold-change comparison showed that

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAnimalsFecal Microbiota TransplantationFecesHumansMiceMuscle StrengthAnaeroplasma abactoclasticumEisenbergiella massiliensisEthanoligenens harbinensefecal microbiome transplantationgut microbiomeIleibacterium valensmuscle strength

Identifiers

PMID38203833
PMCPMC10779158
OpenAlexW4390601549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.