Evidence map›Paper›PMID 38203807›Full record

ArticleInternational journal of molecular sciences2024

Urinary Angiotensinogen Displays Sexual Dimorphism in Non-Diabetic Humans and Mice with Overweight.

Alexis A Gonzalez, Bruna Visniauskas, Virginia Reverte, Ventaka N Sure, Zoe Vallotton, Bryan S Torres, Marco A Acosta, Mahlet Zemedkun, Prasad V Katakam, Minolfa C Prieto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Alexis A GonzalezInstituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340025, Chile.ORCID 0000-0003-0323-1448
Bruna VisniauskasDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0002-4525-2194
Virginia ReverteDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Ventaka N SureDepartment of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0002-3657-962X
Zoe VallottonDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0009-0000-9776-3298
Bryan S TorresDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Marco A AcostaDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Mahlet ZemedkunDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Prasad V KatakamDepartment of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0002-4708-9140
Minolfa C PrietoDepartment of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Tulane University · USPontificia Universidad Católica de Valparaíso · CL

Funding

PLEIOTROPIC EFFECTS OF PRORENIN RECEPOR IN COLLECTING DUCT AND INTRARENAL RAS ACTIVATIONR01DK104375 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI PRIETO, MINOLFA C · 2014 to 2018
$1.7M
NIDDK NIH HHS R01 DK104375NIDDK NIH HHS RO1-DK104375
6 · The paper itself

Abstract

Increased body weight (BW) induces inappropriate renin-angiotensin system (RAS) activation. The activation of the intrarenal RAS is associated with increased urinary angiotensinogen (uAGT), blood pressure (BP), and kidney damage. Here, we examined uAGT excretion levels in young non-diabetic human subjects with overweight (OW) and non-diabetic mice with high-fat diet (HFD)-induced OW. Human subjects (women and men; 20-28 years old) included two groups: (a) overweight (OW,

Indexed as

AngiotensinogenOverweightRenin-Angiotensin SystemSex CharacteristicsAdultAlbuminuriaAnimalsFemaleHumansMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesYoung AdultAngiotensinogenReactive Oxygen Specieshigh-fat dietkidney injury markerssex differencestelemetry

Identifiers

PMID38203807
PMCPMC10779427
OpenAlexW4390587744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.