Evidence map›Paper›PMID 38203712›Full record

ArticleInternational journal of molecular sciences2023

Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.

Emily Jean Wilson, Nagabhishek Sirpu Natesh, Parsa Ghadermazi, Ramesh Pothuraju, Dipakkumar R Prajapati, Sanjit Pandey, Jussuf T Kaifi, John R Dodam, Jeffrey N Bryan, Christian L Lorson and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Emily Jean WilsonDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Nagabhishek Sirpu NateshDepartment of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0003-3826-1591
Parsa GhadermaziDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0009-0005-4112-2105
Ramesh PothurajuDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Dipakkumar R PrajapatiDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-8954-890X
Sanjit PandeyDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Jussuf T KaifiDepartment of Surgery, School of Medicine, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0003-3425-2356
John R DodamDepartment of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65201, USA.
Jeffrey N BryanDepartment of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65201, USA.
Christian L LorsonDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-1023-2169
Aude A WatrelotDepartment of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0003-2411-6529
Jason M FosterDepartment of Surgery, Division of Surgical Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Thomas J MansellDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-8807-4570
Siu Hung Joshua ChanDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-7707-656X
Surinder K BatraDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-9470-9317
Jeyamkondan SubbiahDepartment of Food Science, University of Arkansas, Fayetteville, AR 72701, USA.
Satyanarayana RachaganiDepartment of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65201, USA.
University of Nebraska Medical Center · USUniversity of Missouri · USColorado State University · USIowa State University · USUniversity of Missouri Health System · USUniversity of Arkansas at Fayetteville · USUniversity of Nebraska–Lincoln · US

Funding

Targeting tumor and its microenvironment using nanotherapeutics for pancreatic cancerR01CA247763 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RACHAGANI, SATYANARAYANA · 2020 to 2024
$1.9M
NCI NIH HHS R01 CA247763
6 · The paper itself

Abstract

Gut microbiota plays a crucial role in inflammatory bowel diseases (IBD) and can potentially prevent IBD through microbial-derived metabolites, making it a promising therapeutic avenue. Recent evidence suggests that despite an unclear underlying mechanism, red cabbage juice (RCJ) alleviates Dextran Sodium Sulfate (DSS)-induced colitis in mice. Thus, the study aims to unravel the molecular mechanism by which RCJ modulates the gut microbiota to alleviate DSS-induced colitis in mice. Using C57BL/6J mice, we evaluated RCJ's protective role in DSS-induced colitis through two cycles of 3% DSS. Mice were daily gavaged with PBS or RCJ until the endpoint, and gut microbiota composition was analyzed via shotgun metagenomics. RCJ treatment significantly improved body weight (

Indexed as

ColitisGastrointestinal MicrobiomeInflammatory Bowel DiseasesAnimalsHomeostasisMiceMice, Inbred C57BLcolitisDextran Sodium Sulfate (DSS)gut microbiotainflammatory bowel disease (IBD)red cabbageshort-chain fatty acids (SCFAs)

Identifiers

PMID38203712
PMCPMC10778654
OpenAlexW4390467260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.